Oligohidramniosun Eşlik Ettiği Kistik Higromalı Fetusta Prenatal Tanı: Bir Olgu Sunumu

Kistik higroma, sıvı dolu boşluklardan oluşan, lenfatik sistemin septalı veya septasız olarak izlenebilen konjenital birmalformasyonudur. Bilhassa, Turner Sendromu (45,X0) gibi kromozom anomalileriyle beraber izlenir. Özellikle kis- tik higromalar tarafından komplike edilen gebeliklerde, büyük kistlerin engellemesi veya oligohidramniosun yol aç- tığı zorluklar sebebiyle amniyotik sıvının elde edilememesi üzerine, geleneksel amniyotik sıvı kültürlerinin alternati- fi, kistik higromalardan elde edilen lenfositlerdir. Erken gebelik haftasında olan ve amniyosentezi imkansız kılan oli- gohidroamniosun da eşlik ettiği kistik higromalı bir fetüsün, daha önce literatürde az rastlanan bir şekilde, kistik hig- romasından alınan sıvısında prenatal genetik tanıya ulaşılmıştır. Bu olguyu sunmadaki amacımız, farklı bir prenataltanı yöntemini göstererek literatüre katkı sağlamaktır.

Prenatal Diagnosis in a Fetus with Cystic Higroma Associated with ligohydramnios: A Case Report

Cystic hygroma is acongenital malformation of the lymphatic system that appear as septated or nonseptated fluid- filled cavities. They are often associated with a chromosome abnormality, most commonly Turner Syndrome (45,X0).The serous fluid from the cystic hygromas is a plentiful source of lymphocytes which can be utilized as an alternativeto the traditional amniotic fluid cultures, especially in pregnancies complicated by cystic hygromas in which obtain- ing amniotic fluid sometimes can be very difficult due to the obstructions by large cysts or oligohydramnios. Prenatalgenetic sampling was performed from the fluid taken directly from the cystic hygroma of a fetus in the early gesta- tion associated with oligohydramnios which was making the amniocentesis impossible, in such a way uncommonlyseen in the literature. The purpose of this case is to present a different method of prenatal diagnosis, and thus, make acontribution to the literature.

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