Mine ERDENİZMENLİ, Onur ÖZGENÇ, Ayten URBARLI

6348

The beta-lactamase activities and the resistance patterns of Klebsiella species to antimicrobial agents

With the appearance of extended broad-spectrum beta-lactamases (ESBLs), Klebsiella species gained significance as a nosocomial pathogen. These ESBLs are capable of hydrolyzing newer cephalosporins and monobactams. Although many of the strains do not seem resistant to extended spectrum cephalosporins on the routine laboratory tests, the resistant strains to these beta-lactams could be shown by specific diffusion tests like double disk synergy or three-dimensional tests. Among the 80 Klebsiella isolates from various clinical specimens, the ESBL activities were found 55 and 58.7% with double disk diffusion and three-dimensional tests, respectively. The most common foci for such infections were the urinary tract, respiratory tract and surgical wound sites. Klebsiella species were found resistant to various antibiotics in different percentages. The most resistant strains appeared to have arisen in the intensive care unit.
Medical Journal of Ege University-Cover
  • ISSN: 1017-7698
  • Yayın Aralığı: 3
  • Başlangıç: 2018
  • Yayıncı: Ege Üniv. Tıp Fak.
Arşiv
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