Gürhan KADIKÖYLÜ, Celalettin CAMCI, H. Meltem SÖNMEZ, Ayşin ÖGE, A. Zahit BOLAMAN, Taşkın ŞENTÜRK

TİP-II DİABETTE ASEMPTOMATİK KOLELİTİAZİS SIKLIĞI

Anahtar Kelimeler:

Kolelitiazis , Tip-II diabet

The Prevalence of Asymptomatic Cholelithiasis in Type-II Diabetes Mellitus

Objective: To evaluate the prevalence of asymptomatic cholelithiasis in type-II diabetes. Method: Abdominal ultrasonography was performed on 138 patients with type-II diabetes (100 women and 38 men) over 35 years old 270 people (190 women and 80 men) over 35 years old were examined as the control group. Results: 17 of the patients (12.3 %) and 28 controls (10.3 %) had cholelithiasis. These rates weren’t statisti-cally different (p>0.05). 13 % of female patients and 10.5 % of men patients were found that they had cholelithiasis. These rates were 11 % and 8.75 % in the control group . There was no statistically significant difference between these groups either (p > 0.05). Conclusion: The prevalance of asymptomatic cholelithiasis in type-II diabetes was not different than that of healthy persons.

Keywords:

Cholelithiasis, Type-II diabetes,

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1. Leichter RF, Pellegreni CA. Cholelithiasis and cholecystitis. In: Rakel RE (ed). Conn’s Current Therapy. Philadelphia: WB Saunders Company, 1993: 445-6.
2. Vlahcevic ZR, Heuman DM. Diseases of the gallbladder and bile ducts. In: Bennett JC, Plum F (eds). Cecil Textbook of Medicine, 20th ed. Philadelphia: W.B. Saunders Company. 1996: 805-16.
3. Greenberger NJ, Isselbacher KJ. Diseases of the gallbladder and bile ducts. In: Fauci AS, Braunwald E, Isselbacher KJ, Wilson JD, Martin JB, Kasper DL, Hauser DL, Longo DL (eds). Harrison’s Principle Internal Medicine, 14th ed. New York: Mc Graw Hill Comp, 1998: 1725-36.
4. Beyler AR, Uzunalimoðlu Ö, Gören A, Özden A, Sipahi N, Kesim E, Dökmeci A. Türkiyede normal populasyonda safra kesesi taþý prevalansý . Gastroenteroloji 1993; 4: 434-7.
5. Özütemiz Y, Batur T, Özgüven Ö. Ege bölgesinde sessiz safra kesesi taþý prevalansý. Klinik Geliþim 1992; 5: 1737-41.
6. Lieber MM. The incidence of gallstones of their correlation with other disease. Am Surg 1952; 135: 394-409.
7. Bertoli E, Ferrari E, Saporetti N, Rossi L. Prevalence of cholelithiasis in diabetes. A cholecystosonographic study. Rays 1987; 1: 43-46.
8. Haffner SM, Diehl AK, Mitchell DD, Stern MP, Hazuda HP. Increased prevalence of clinical gallbladder disease in subjects with non-insulin dependent diabetes mellitus. Am J Epidem 1990; 132: 327-35.
9. Foster KJ, Griffith SH, Dewberg K. Liver disease in patients with diabetemellitus. Postgrad Med J 1990; 5: 767-72.
10. Jörgensen T. Gallstones in Danish population, Relation to weigth, physicalactivity,smoking, coffee consumption and diabetes mellitus. Gut 1989; 1: 528-34.
11. Feldman M. The incidence of cholelithiasis and liver disease in diabetesmellitus. An autopsy study. Diabetes 1954; 3: 305-7.
12. Zaher Z, Sternby NH, Kagan A et al. Frequency of cholelithiasis in Prague and Malmö An autopsy study. Scand J Gastroenterology 1974: 9; 3-7.
13. Twiss JR, Carter RF. The relationship of biliary tract disorders to diabetes mellitus. Am J Sci 1942; 224: 263- 73.
14. Hanis CL, Ferrel RE, Tulloch BR, Schull WJ. Gallbladder disease epidemiology in Mexican Americans in Texas. Am J Epidem 1985 ; 22: 820-29.
15. Mc Sherry CK, Ferstenberger H, Salbaun WF, Lahman E,Virshup M. Natural history of diagnosed gallstone disease in symptomatic patients. An Surg 1989; 20:59-63.
16. Lu SN, Chang WY, Wang LY. Risk factors gallstones among Chineese in Taiwan. A community sonographic survey. J Clin Gastroenterology 1992; 12: 542-6.
17. Persson GE, Thulin JC. Prevalence of gallstone disease in patients with diadiabetes mellitus. Eur J Surg 1991; 157: 579-82.
18. Janatuinen E, Pikkaurainen P, Laaksom M, Pyörala K. Gastrointestinal symptoms in middle aged diabetic patients. Scand J Gastoenterology 1993; 38: 427-32.
19. Braverman DZ. The lack of metocloropropamide on gallbladder volume and contraction in diabetic cholecystoparesis. Am J Gastroenterology 1986; 8: 960-2.
20. Keshavarzian A. Gastrointestinal involment insulin requiring diabetes mellitus. J Clin Gastroenterology 1987; 9: 685-92.
21. Kalser MH, Schoenfield LJ, Marks JW, Tompkins RK. Cholelithiasis. In: Berk JE (ed). Cholelithiasis, Philadelphia: WB Saunders Comp, 1987: 3619-42.
22. Stone BG, Gavater JS, Belle SH. Impairement of gallbladder emptying in diabetes mellitus. Gastroenterology 1988; 95: 170-6.
23. Haber GB, Heaton KW. Lipid consumption of bile diabetics,obesity,matched controls. Gut 1979; 20: 518- 21.
24. Ponz de LM, Ferender R, Carulli N. Bile lipid cosumption and bile acid pool size in diabetes. Am Dig Dis 1978; 23: 710-6.
25. Scragg RKR, Calvert GD, Oliver JR. Plasma lipids and insulin in gallstone disease, A case control study. BMJ 1984; 89: 521-5.
26. Ahlberg J.Serum lipid levels and hiperlipo-proteinemia in men with gallstone disease. Acta Clin Scand 1979; 145: 373-7.
27. Pettiti DB, Friedman GD, Klatsky AL. Association of history of gallbladder disease with reduced concentration of high density lipoprotein cholesterol. N Eng J Med 1981; 304: 1396-8 .
28. Laakkso M, Suhanon M, Julkýnen R, Pyöralak M. Plasma insulin, serum lipids and lipoproteins in gallstone disease in non-insulin dependent diabetic sub jects. A case control study. Gut 1990; 31: 344-7.
29. Laakkso M, Pyöralak M, Voutilairen E. Plasma insulin and serum lipids and lipoprotein in mddle aged noninsulin dependent diabetic and nondiabetic patients. Am Epidem 1987: 1; 611-21.
30. Güneri S, Koþay S, Þimþek I. Diabetes mellitusta safra kesesi taþý insidansý. Dokuz Eylül Üniversitesi Týp Fakültesi Dergisi. 1997; 2: 9-14.