İDİL BAŞTAN, Seçkin SALAR, AYHAN BAŞTAN, MERT PEKCAN, TEVHİDE SEL

Türk Saanen Keçilerinde Geçiş Dönemi Boyunca Metabolik Parametreler ve Paraoksonaz-1 Değişiminin İncelenmesi

Bu çalışmanın amacı, Türk Saanen keçilerinde geçiş dönemi boyunca metabolik parametreler ve paraoksonaz-1 düzeylerindeki değişimi incelenmekti. Çalışmada 60 adet Türk Saanen keçisi ve bu keçilerin juguler venasından doğumdan 30 ve 15 gün önce, doğumda ve doğumdan 15 ve 30 gün sonra alınan kan örnekleri kullanıldı. Metabolik profilde meydana gelen değişimleri belirlemek için alkalen fosfataz (ALP), kolesterol (CHO), glukoz (GLU), kalsiyum (CA), fosfor (PHO), total protein (TOP), trigliserit (TG), paraoksonaz-1 (PON-1), ?-hidroksibütirik asit (BHBA) ve non-esterifiye yağ asidi (NEFA) düzeyleri belirlendi. Serum alkalen fosfataz düzeyleri -30, 0 ve +15. günlerde en düşük, +30. günde en yüksekti (P

Investigation of Changes in Metabolic Parameters and Paraoxonase-1 During the Transition Period in Turkish Saanen Goats

The aim of this study was to evaluate the metabolic changes and PON-1 levels in Turkish Saanen goats during the transition period. In the study, 60 Turkish Saanen goats were used and blood samples were taken from the jugular vein on days -30, -15, 0, +15, and +30 from parturition. In order to monitor metabolic profile changes, alkaline phosphatase (ALP), cholesterol (CHO), glucose (GLU), calcium (CA), phosphorus (PHO), total protein (TOP), triglyceride (TG), paraoxonase-1 (PON-1), ?-hydroxybutyric acid (BHBA) and non-esterified fatty acid (NEFA) levels were determined. Serum alkaline phosphatase levels were lower on days -30, 0 and +15, and higher on day +30 (P<0.001). Serum cholesterol and total protein levels were lower on days -30 and 0, and higher on day +30 (P<0.001). Serum levels of glucose, calcium and phosphorus were lower on day 0, and higher on day +30 (P<0.001). Serum triglyceride levels were lower on days -15 and 0, and higher on days -30 and +30 (P<0.05). Serum paraoxonase-1 levels were lower on day 0, and higher on day -30 (P<0.05). Serum ?-hydroxybutyric acid levels were lower on day -30, and higher on day +15 (P<0.05). Serum non-esterified fatty acid levels were lower on days -30 and +30, and were higher on days -15 and 0 (P<0.001). In conclusion, the results of our study showed that clear changes in levels of metabolic parameters and PON-1 were seen during the transition period in Turkish Saanen goats.

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