CİHAN KAÇAR, MEHMET ÇİTİL, MAHMUT KARAPEHLİVAN, SAVAŞ YILDIZ, METİN ÖĞÜN, HİDAYET METİN ERDOĞAN

The effect of L-carnitine injection at prepartum period on the plasma IgG level and gamma-glutamyltransferase (GGT) activity in cows and calves

Bu çalışmada, gebeliğin son üç haftasında ve doğumda L-carnitine uygulanan inekler ve bunların buzağılarında plazma IgG ve GGT seviyesi araştırıldı. Çalışma 20 adet inek ve bunların buzağılarında yapıldı. Hayvanlar iki eşit gruba ayrıldı. L-carnitine uygulanan ineklere, gebeliğin son üç haftasından doğuma kadar birer hafta aralıklarla ve doğumun gerçekleştiği gün (0. gün) 1 g/hayvan/gün dozunda Lcarnitine subkutan yolla uygulandı. Kontrol grubundaki ineklere ise subkutan yolla placebo uygulandı. Bütün inekler ve yeni doğan buzağılardan doğumdan sonraki 1 ve 3. günlerde kan alındı. Alınan kanlarda IgG, total protein, albumin ve GGT seviyelerine bakıldı. İki gruptaki ineklerde benzer sonuçlar bulundu. Lcarnitine uygulanan ineklerin buzağılarında 1 ve 3. günlerdeki GGT oranının kontrol grubu buzağılarına göre yüksek olduğu tespit edildi. IgG seviyesinin 1. günde kontrol grubu buzağılarda, 3. günde ise Lcarnitine uygulanan ineklerin buzağılarında daha yüksek olduğu görüldü. Sonuç olarak gebe ineklerde Lcarnitine uygulamalarının ne ineklerde ne de bu ineklerin yeni doğan buzağılarında IgG, GGT, total protein ve albumin parametrelerinde önemli bir değişikliğe yol açmadığı kanısına varıldı.

Anahtar Kelimeler:

gama-glutamiltransferaz, IgG, buzağı, karnitin, inek

Prepartum dönemde L-carnitine enjeksiyonlarının, inek ve buzağılarda plazma IgG düzeyi ve gamma-glutamyltransferase (GGT) aktivitesine etkisi

This study investigated the effect of L-carnitine on IgG and GGT levels in cows receiving L-carnitine during the last three weeks of pregnancy and on the parturition and their newborn calves. The study involved 20 cows and their calves. Animals were divided into two equal groups; cows in L-carnitine group subcutaneously received 3 injections of 1g/cow/day of L-carnitine weekly intervals during the last three weeks of gestation, at the parturition (0 day) and control group received placebo during the same period. All cows and newborn calves were blood sampled on the 1 and 3 days after birth in order to determine IgG, total protein and albumine and GGT concentrations. The concentrations of IgG, total protein, albumine, and GGT. The values were similar in cows of both groups but calves in L-carnitine group had higher GGT levels on day 1 and 3 and IgG level on day 3 whereas IgG level was higher in control calves on day 1. As a result, L-carnitine injection in pregnant cows did not cause a significant change in IgG, GGT, total protein and albumine levels in cows and their newborn calves.

Keywords:

gamma-glutamyltransferase, IgG, calves, carnitine, cows,

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