Hüseyin CİHAN, Ethem Mutlu TEMİZEL, ZEKİ YILMAZ, Yeşim ÖZARDA

Serum Iron Status and Its Relation with Haematological Indexes Before and After Parturition in Sheep

Eritrosit belirteçleri, total demir bağlama kapasitesi (TIBC) ve demir bağlama kapasitesi (UIBC) değerleri demir eksikliği durumları ve inflamatuar hastalıklarda, aneminin tanısı için önemli bilgiler sağlar. Bu çalışmanın amacı, doğum öncesi ve sonrası koyunlarda serum demir durumu ve hematolojik endekslerle ilişkisini değerlendirmektir. Serum demir seviyesi (SI), TIBC, UIBC ve hematolojik parametreleri belirlemek üzere kan örnekleri aynı yaş ve barındırılma koşullarındaki gebe (n=30) ve gebe olmayan (n=30) İvesi koyunlarından doğumdan tahmini 1 hafta (±2 gün) önce, doğum zamanı ve doğumdan 1 gün sonra ve 1, 2, 3, 4, 6, 8 ve 12. haftalarda toplandı. Eritrosit (RBC), hematokrit (Hct) değer ve hemoglobin (Hb) seviyeleri postpartum dönemin 12. haftasına doğru (P

Koyunlarda Doğum Öncesi ve Sonrası Serum Demir Durumu ve Hematolojik Endekslerle İlişkisi

Erythrocyte indices, total iron binding capacity (TIBC) and unsaturated iron binding capacity (UIBC) values provide important information for the diagnosis of anaemia in iron deficiency conditions and inflammatory diseases. The aim of this study was to evaluate the serum iron status and its relation with haematological indexes before and after parturition in sheep. Blood samples were collected from pregnant (n=30) and non-pregnant aged-matching Ivesi sheep (n=30), housed under the same conditions, at 1 week (wk) (±2 days) before expected parturition, in parturition (baseline), at day 1 and at 1, 2, 3, 4, 6, 8 and 12th wk subsequent to the parturition, to determine the serum levels of iron (SI), TIBC and UIBC as well as the haematological parameters. Erythrocyte (RBC) count, haematocrit (Hct) and haemoglobin (Hb) values dropped at 12 wk (P<0.05) according to 1 wk (±2 days) before expected parturition and during parturition. Mean corpuscular volume concentrations were also found lower (P<0.05) at 4-12 wk after parturition, in comparison with their baselines. After the parturition, SI concentration decreased at day 1 (P<0.05) and then remained low (P<0.05) during the study. TIBC was higher for the first 2 wk, but was lower at 6-12 wk compared with its baseline (P<0.05). UIBC values were in parallel to TIBC values after the parturition. In conclusion; negative effects on leukocytes of metabolic stress after delivery should be taken into consideration, as it can trigger the potential problems during this period. In postpartum period, SI levels along with erythrocyte indices can be useful parameters to follow the iron loss by fetus and colostrum. Incompatible results of TIBC and UIBC levels with SI and erythrocyte indices in this study showed that TIBC and UIBC may not be useful biomarkers to evaluate serum iron values, particularly in postpartum period.

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