ÖZLEM ÖNEN ÇELEBİ, Özge GÜNDÜZ, SEMA İŞİSAĞ ÜÇÜNCÜ

Ham Petrolün Suda Çözünebilen Kısımlarının Pelvicachromis pulcher (Boulenger, 1901) (Cichlidae, Teleostei) Bağırsak ve Karaciğeri Üzerindeki Etkileri [1]

Petrokimyasal üretim süreçlerinin sağlığımız ve çevremiz üzerindeki zararlı etkilerinin ortaya konmasına katkıda bulunmak amacıyla, 15 gün süreyle %40'lık subletal konsantrasyonda ham petrolün suda çözünebilen kısımlarına maruz bırakılan bir teleost türünün, Pelvicachromis pulcher'in bağırsak ve karaciğer dokularında gözlenen histopatolojik değişimler ışık mikroskobu ile araştırıldı. Kontrol grubuyla karşılaştırıldığında, ham petrole maruz bırakılan örneklerin bağırsaklarında göze çarpan ülserasyon, deskuamasyon, lenfosit infiltrasyonu ve nekroz gibi ciddi histolojik değişimler not edildi. Karaciğerde steatosis, hemoraji, sinüzoidlerde genişleme ve özellikle piknotik ve karyoretik nukleuslarla karakterize edilen çarpıcı hepatosellüler bozulma olarak ayırt edilen belirgin deformasyonlar gösterdiği tespit edildi. Ham petrolün suda çözünebilen kısımlarının her iki dokuda da, beklenildiği üzere önemli ölçüde etkili olduğu sonucuna varıldı.

The Eff ects of Water Soluble Fractions of Crude Oil on The Intestine and Liver of Pelvicachromis pulcher (Boulenger, 1901)

In order to make a contribution to displaying of the harmful eff ects of the petrochemical production processes to our health and environment, it has been investigated the histopathological changes obseved in the intestine and hepatic tissues of Pelvicachromis pulcher, a teleost fish, after a 15-day exposure to 40% sublethal concentrations of the water-soluble fractions of crude oil, by light microscopy. Several histological alterations such as prominent ulceration, desquamation, lymphocyte infiltration and necrosis, were noted for the intestinal tissue of the crude oil exposed animals when compared with controls. The liver was also shown marked deformative changes identified as steatozis, hemorrhage, dilatation of sinusoids and pronounced hepatocellular degeneration which was specially characterized pyknotic and karyorrhetic nuclei. It was concluded that the water soluble fractions of crude oil was drastically eff ected both of the tissues studied, as expected.

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