Türkiye'de Vona kıyısından toplanan Clorophyceae (Cladophora glomerata, Enteromorpha linza, Ulva rigida), Phaeophyceae (Cystoseira barbata, Padina pavonica) ve Rhodophyceae (Corallina officinalis, Ceramium ciliatum) familyalarına ait yedi deniz alg türünden elde edilen etanol ektraktlarının altı bakteri ve iki fungusa karşı in vitro koşullarda antibakteriyel ve antifungal aktiviteleri kağıt disk difüzyon metodu ile değerlendirilmiştir. Deniz alglerinin analizi sonucunda Cladophora glomerata ve Padina pavonica türleri test edilen organizmalara karşı en yüksek aktiviteye sahip olduğu görülmüştür. Özellikle, Enteromorpha linza ve Padina pavonica, Aspergillus niger türüne karşı en yüksek fungal aktiviteyi gösterirken Cladophora glomerata ise Staphylococcus aureus türüne karşı en yüksek antibakteriyel aktiviteyi göstermiştir. Bunun yanısıra tüm alg türlerinin ekstraktları Staphylococcus aureus, Salmonella typhimurium ve Aspergillus niger türlerine karşı yüksek derecede antimikrobiyal aktivite gözlenmiştir. Enteromorpha linza ve Padina pavonica'dan elde edilen kuru ektraktların minimal inhibisyon konsantrasyonu (MİK) sırasıyla 2.5-10 mg/ml ve 1.25-10 mg/ml değişen aralıktadır.
Ethanolic crude extracts from seven marine algal species belong to Clorophyceae (Cladophora glomerata, Enteromorpha linza, Ulva rigida), Phaeophyceae (Cystoseira barbata, Padina pavonica) and Rhodophyceae (Corallina officinalis, Ceramium ciliatum) from the coast of Vona, Turkey were evaluated in vitro for the antibacterial and antifungal activity of six bacteria and two fungus with the paper disc agar diff usion methods. The marine algae analysed of Cladophora glomerata and Padina pavonica were the species with the strongest activities against the broadest spectrum of test organisms. In particular, Enteromorpha linza and Padina pavonica showed the highest antifungal activity against Aspergillus niger, while Cladophora glomerata showed the highest antibacterial activity against Staphylococcus aureus. On the other hand, it was found that extracts of all marine algae were significant antimicrobial activity against Staphylococcus aureus, Salmonella typhimurium and Aspergillus niger. The minimal inhibition concentrations (MIC) of the crude extract obtained from Enteromorpha linza and Padina pavonica ranged from 2.5 to 10 mg/ml and 1.25 to 10 mg/ml, respectively.
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