This experiment was conducted to investigate the accelerator effect of coral and platelet rich fibrin (PRF) on bone healing in rabbits (n=12) with clinically, radiologically, and histologically. The rabbits were divided randomly into two groups. There were two bone defects (3.5 mm diameter) created bilaterally on the proximal part of the tibia of rabbits. In control group, the defects were left empty. The other defects (twelve defects in each group) were filled with coral, PRF and coral plus PRF. Postoperatively, on the 30th and 60th days, clinical, radiographic and histologic examinations were performed. On the radiological examinations, bone healing was better seen in the grafted groups than in the control group (P
Bu deney, tavşanlarda (n=12) mercan ve trombosit açısından zengin fibrinin (TZF) kemik iyileşmesi üzerindeki hızlandırıcı etkisini klinik, radyolojik ve histolojik olarak araştırmak amacıyla yapıldı. Tavşanlar rastgele iki gruba ayrıldı. Tavşanların tibialarının proksimalinde bilateral olarak iki kemik defekti (3.5 mm çapında) oluşturuldu. Kontrol grubundaki defektler boş bırakıldı. Diğer defektler (her grupta oniki defekt) mercan, TZF ve mercan ve TZF ile dolduruldu. Operasyon sonrası, 30 ve 60. günlerde klinik, radyografik ve histolojik muayeneler yapıldı. Radyolojik incelemelerde greftli gruplarda kemik iyileşmesi kontrol grubuna göre daha iyi olduğu gözlendi (P
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