Atretic Ovarian Follicles Morphology and Immunolocalization of Active Caspase-3 in Algerian Bedouin Goat (Capra hircus) Ovaries

This study aims to highlight the cellular and molecular events of atresia in the Bedouin goat ovarian follicles. Ovaries collected from slaughterhouses during breeding and non-breeding seasons were submitted to morphological studies and immunolocalization of active caspase-3. The results showed that ovaries were heavier (P

Cezayir Bedevi Keçisi (Capra hircus)’nde Atretik Ovaryum Folikül Morfolojisi ve Aktif Kaspaz-3 İmmunolokalizasyonu

Bu çalışmada Bedevi keçisi ovaryum foliküllerinde gelişen atrezide meydana gelen hücresel ve moleküler olaylar tanımlanmıştır. Çiftleşme sezonunda veya dışında kesimhanelerden toplanan ovaryumlar morfolojik çalışmalar ve aktif kaspaz-3 immunolokalizasyonu için kullanıldı. Elde edilen sonuçlar ovaryumların çiftleşme sezonunda daha ağır olduğunu gösterdi (P

___

Silanikove N: The physiological basis of adaptation in goats to harsh environments. Small Ruminant Res, 35 (3): 181-193, 2000. DOI: 10.1016/ S0921-4488(99)00096-6

Charallah S, Amirat Z, Sulon J, Khammar F, Beckers JF: Pregnancyassociated glycoprotein and progesterone concentrations during pregnancy failure in Bedouin goat from the southwest of Algeria. Reprod Domest Anim, 45 (6): e231-e238, 2010. DOI: 10.1111/j.1439-0531.2009.01511.x

Malek M, Amirat Z, Khammar F, Khaldoun M: Analysis of the energetic metabolism in cyclic Bedouin goats (Capra hircus): Nychthemeral and seasonal variations of some haematochemical parameters in relation with body and ambient temperatures. J Therm Biol, 60, 86-94, 2016. DOI: 10.1016/j.jtherbio.2016.06.005

Chergui N, Mormede P, Foury A, Khammar F, Amirat Z: Seasonal effects on plasma cortisol concentrations in the Bedouin buck: Circadian studies and response to ACTH. Animal, 11 (3): 445-451, 2017. DOI: 10.1017/S1751731116001671

Haque Z, Haque A, Quasem MA: Morphologic and morphometric analysis of the ovary of Black Bengal goat (Capra hircus). Int J Morphol, 34 (1): 13-16, 2016. DOI: 10.4067/S0717-95022016000100002

Wang W, Liu HL, Tian W, Zhang FF, Gong Y, Chen JW, Mao DG, Shi FX: Morphologic observation and classification criteria of atretic follicles in guinea pigs. J Zhejiang Univ Sci B, 11 (5): 307-314, 2010. DOI: 10.1631/ jzus.B0900391

Manabe N, Goto Y, Matsuda-Minihata F, Inoue N, Maeda A, Sakamaki K, Miyano T: Regulation mechanism of selective atresia in Porcine follicles: Regulation of granulosa cell apoptosis during atresia. J Reprod Develop, 50 (5): 493-514, 2004. DOI: 10.1262/jrd.50.493

Zhang J, Liu Y, Yao W, Li Q, Liu HL, Pan Z: Initiation of follicular atresia: gene networks during early atresia in pig ovaries. Reproduction, 156 (1): 23-33, 2018. DOI: 10.1530/REP-18-0058

Shi Y: Caspase activation, inhibition, and reactivation: A mechanistic view. Protein Sci, 13 (8): 1979-1987, 2004. DOI: 10.1110/ps.04789804

Berardinelli P, Russo V, Martelli A, Nardinocchi D, Giacinto OD, Barboni B, Mattioli M: Colocalization of DNA fragmentation and caspase-3 activation during atresia in pig antral follicles. Anat Histol Embryol, 33, 23-27, 2004. DOI: 10.1111/j.1439-0264.2004.00504.x

Boatright KM, Salvesen GS: Mechanisms of caspase activation. Curr Opin Cell Biol, 15 (6): 725-731, 2003. DOI: 10.1016/j.ceb.2003.10.009

Gown AM, Willingham MC: Improved detection of apoptotic cells in archival paraffin sections: Immunohistochemistry using antibodies to cleaved caspase 3. J Histochem Cytochem, 50 (4): 449-454, 2002. DOI: 10.1177/002215540205000401

Escobar ML, Echeverria OM, Vazquez-Nin GH: Role of autophagy in the ovary cell death in mammals. In, Autophagy- A double-edged sword - cell survivalor death? InTech, 423-441, 2013.

Yang Z, Klionsky DJ: An overview of the molecular mechanism of autophagy. Curr Top Microbiol Immunol, 335, 1-32, 2009. DOI: 10.1007/ 978-3-642-00302-8_1

Xu J, Wang Y, Tan X, Jing H: MicroRNAs in autophagy and their emerging roles in crosstalk with apoptosis. Autophagy, 8 (6): 873-882, 2012. DOI: 10.4161/auto.19629

Rodgers RJ, Irving-Rodgers HF: Morphological classification of bovine ovarian follicles. Reproduction, 139 (2): 309-318, 2010. DOI: 10.1530/REP-09-0177

Tizhe MA, Kubkomawa HI, Butswat IRS, Addass PA, Kwaji DT: Characterization of reproductive organs of female goats in Guinea Savannah Zone of North-Eastern Nigeria. Sky J Agric Res, 4 (3): 47-59, 2015.

Bari MA, Kabir ME, Sarker MB, Khan AHNA, Moniruzzaman M: Morphometric analysis of ovarian follicles of Black Bengal goats during winter and summer season. Bang J Anim Sci, 39 (1-2): 51-55, 2011. DOI: 10.3329/bjas.v40i1-2.10791

Ramsingh L, Sadasivarao K, Muralimohan K: Ovarian biometrics and oocyte grading percentage of yield in local goats of Andhra Pradesh. Iosr J Pharm, 3 (1): 47-49, 2013. DOI: 10.9790/3013-31304749

Islam MR, Khandoker MAMY, Afroz S, Rahman MGM, Khan RI: Qualitative and quantitative analysis of goat ovaries, follicles and oocytes in view of in vitro production of embryos. J Zhejiang Univ Sci B, 8 (7): 465- 469, 2007. DOI: 10.1631/jzus.2007.B0465

Logothetopoulos J, Dorrington J, Bailey D, Stratis M: Dynamics of follicular growth and atresia of large follicles during the ovarian cycle of the guinea pig: Fate of the degenerating follicles, a quantitative study. Anat Rec, 243 (1): 37-48, 1995. DOI: 10.1002/ar.1092430106

Boone DL, Tsang BK: Caspase-3 in the Rat ovary: Localization and possible role in follicular atresia and luteal regression. Biol Reprod, 58, 1533-1539, 1998.

Sugimoto M, Manabe N, Kimura Y, Myoumoto A, Imai Y, Ohno H, Miyamoto H: Ultrastructural changes in granulosa cells in Porcine antral follicles undergoing atresia indicate apoptotic cell death. J Reprod Develop, 44 (1): 7-14, 1998. DOI: 10.1262/jrd.44.7

Matikainen T, Perez GI, Zheng TS, Kluzak TR, Rueda BR, Flavell RA, Tilly JL: Caspase-3 gene knockout defines cell lineage specificity for programmed cell death signaling in the ovary. Endocrinology, 142 (6): 2468-2480, 2001. DOI: 10.1210/endo.142.6.8078

Fenwick MA, Hurst PR: Immunohistochemical localization of active caspase-3 in the mouse ovary: growth and atresia of small follicles. Reproduction, 124, 659-665, 2002. DOI: 10.1530/rep.0.1240659

Vlckova R, Sopkova D, Posivak J, Valocky I: Ovarian follicular atresia of ewes during spring puerperium. Vet Med Int, 2012:638928, 2012. DOI: 10.1155/2012/638928

Lin P, Yang Y, Li X, Chen F, Cui C, Hu L, Li Q, Liu W, Jin Y: Endoplasmic reticulum stress is involved in granulosa cell apoptosis during follicular atresia in goat ovaries. Mol Reprod Dev, 79 (6): 423-432, 2012. DOI: 10.1002/mrd.22045

Sharma RK, Bhardwaj JK: Ultrastructural characterization of apoptotic granulosa cells in caprine ovary. J Microsc, 236 (3): 236-242, 2009. DOI: 10.1111/j.1365-2818.2009.03281.x

Hay MF, Cran DG, Moor RM: Structural changes occurring during atresia in sheep ovarian follicles. Cell Tissue Res, 169, 515-529, 1976. DOI: 10.1007/BF00218150

Fuku E, Xia L, Downey BR: Ultrastructural changes in bovine oocytes cryopreserved by vitrification. Cryobiology, 32 (2): 139-156, 1995. DOI: 10.1006/cryo.1995.1013

Kerr JFR, Wyllie AH, Currie AR: Apoptosis: A basic biological phenomen with wide-ranging implicatons in tissue kenetics. Br J Cancer, 26, 239-257, 1972.

Silva JRV, Ferreira MAL, Costa SHF, Santos RR, Carvalho FCA, Rodrigues APR, Lucci CM, Báo SN, Figueiredo JR: Degeneration rate of preantral follicles in the ovaries of goats. Small Ruminant Res, 43 (3): 203- 209, 2002. DOI: 10.1016/s0921-4488(02)00017-2

Yoshinaga-Hirabayashi T, Osawa Y: Steroidogenic activity of atretic follicles in the cycling hamster ovary and relation to ultrastructural observations. Histochemistry, 102 (1): 59-67, 1994. DOI: 10.1007/BF00271050

Wu X, Chen L, Brown CA, Yan C, Matzuk MM: Interrelationship of growth differentiation factor 9 and inhibin in early folliculogenesis and ovarian tumorigenesis in mice. Mol Endocrinol, 18 (6): 1509-1519, 2004. DOI: 10.1210/me.2003-0399

O’Shea JD, Hay MF, Cran DG: Ultrastructural changes in the theca interna during follicular atresia in sheep. J Reprod Fert, 54, 183-187, 1978.

Hussein MR: Apoptosis in the ovary: Molecular mechanisms. Hum Reprod Update, 11 (2): 162-178, 2005. DOI: 10.1093/humupd/dmi001

Hughes FM, Gorospe WC: Biochemical identification of apoptosis (programmed cell death) in granulosa cells: Evidence for a potential mechanism underlying follicular atresia. Endocrinology, 129 (5): 2415- 2422, 1991. DOI: 10.1210/endo-129-5-2415

Billig H, Furuta I, Hsueh AJW: Estrogens inhibit and androgens enhance ovarian granulosa cell apoptosis. Endocrinology, 133 (5): 2204- 2212, 1993. DOI: 10.1210/endo.133.5.8404672

Kassouri S, Boukenaoui N, Charallah S, Amirat Z, Khammar F: Immunolocalization of androgen receptor in the ovary of the Bedouin goat (Capra hircus) in non- breeding season. In, Farooq SA, Abed R, Baqır S (Eds): Biotechnology and Consrvation of Species from Arid Regionsed. Nova Science Publishers, New York, USA, 2014.

Uslu B, Dioguardi CC, Haynes M, Miao DQ, Kurus M, Hoffman G, Johnson J: Quantifying growing versus non-growing ovarian follicles in the mouse. J Ovarian Res, 10:3, 2017. DOI: 10.1186/s13048-016-0296-x
Kafkas Üniversitesi Veteriner Fakültesi Dergisi-Cover
  • ISSN: 1300-6045
  • Yayın Aralığı: Yılda 6 Sayı
  • Başlangıç: 1995
  • Yayıncı: Kafkas Üniv. Veteriner Fak.
Sayıdaki Diğer Makaleler

Yerel Irk Bir Kısrakta Böcek Sokmasına Bağlı Aşırı Duyarlılık (Tatlı Kaşıntı)

Ejaz AHMAD, Tanveer AHMAD, Muhammad Saleem AKHTAR, Muhammad Mazhar AYAZ, Muhammad Mudassar NAZIR, Muhammad Raza HAMEED, Maqbool HUSSAIN

Incarvillea emodi (Royle ex Lindl.) Chatterjee’nin Bazı Biyolojik Etkilerinin Değerlendirilmesi ve Aktif Bileşiklerinin Tayini

İclal SARAÇOĞLU, Vahap Murat KUTLUAY, Zeynep DOĞAN, Yasir IHTESHAM, Uzma KHAN

Solunum Sistemi Hastalığı Olan Buzağılarda Saptanan Bovine Respiratory Syncytial Virusun Filogenetik Analizi

Nüvit COŞKUN, Feray ALKAN, İlke KARAYEL HACIOĞLU, Selda DURAN YELKEN, Seçil SEVİNÇ

Study of FecXG Polymorphism in Beetal Goat and Its Phylogenetic Relationship

Atia BASHEER, Mehwish SHAREEF, Mahjabeen ISLAM, Imran ZAHOOR

The Effect of Rocuronium and Sugammadex on Progesterone Levels in Pregnant Rabbits Under General Anesthesia

RUKİYE TÜRK, SEMRA KAYA, İlksen DÖNMEZ, İSA ÖZAYDIN, OĞUZ MERHAN, Sadık YAYLA, Celal Şahin ERMUTLU, CİHAN KAÇAR, Uğur AYDIN, ÖZGÜR AKSOY, Ürfettin HÜSEYİNOĞLU

Sığır İn Vitro Embriyo Üretiminde Sistamin ve 13-Cis-Retinoik Asitin Etkisi

Mehran Farhoodi MOGHADAM, Abdolreza RANJBAR, Mohammad Amin ESLAMPOUR

Effect of Multi-enzyme Produced By a Single Fungus on Growth Performance and Some Carcass Parameters of Broiler Chicks Fed on Maize-Soya Based Diets

Hasan rüştü KUTLU, Seyyed Naeim SABER, Harun KUTAY, Ladine ÇELİK, Yusuf UZUN, Nurten TOY, Metehan KUTLU, Özcan YÜCELT, Aykut BURĞUT, Pascal THIERY, Barış YAVUZ

Sıradışı Bir Fötal Ölüm: Terrier Bir Köpekte İnguinal Herni

Semra KAYA, Murat Can DEMİR, Hasan ORAL, Mushap KURU

Isolation of Ampicillin and Vancomycin Resistant Enterococcus faecium from Dogs and Cats

Özkan ASLANTAŞ, Erhan TEK

Cezayir Bedevi Keçisi (Capra hircus)’nde Atretik Ovaryum Folikül Morfolojisi ve Aktif Kaspaz-3 İmmunolokalizasyonu

Nouria BOUKENAOUI-FERROUK, Farida KHAMMAR, Sara KASSOURI-MAOUCHE, Salima CHARALLAH, Asma CHAKHMA, Elara MOUDILOU, Zaina AMIRAT, Jean-Marie EXBRAYAT