Funda YILDIRIM, Aydın GÜREL, Yalçın DEVECİOĞLU, EBRU ERAVCI, Kaan DÖNMEZ

Congenital segmental hypoplasia of the spinal cord in A Holstein calf

Bu olguda 40 günlük Holstein ırkı bir buzağıda segmental hipoplazi tanımlanmıştır. Buzağı doğum sonrası ayağa kalkamama şikâyeti ile kliniklerimize (İstanbul Üniversitesi, Veteriner Fakültesi, Eğitim ve Araştırma Hastanesi, Cerrahi Kliniği) getirildi. Klinik ve radyolojik muayene sonrasında 3. ve 4. lumbal vertebralar hizasında omurilikte anormallik saptandı. Prognozun kötüleşmesi üzerine buzağıya ötenazi ve sistemik nekropsi uygulandı. Makroskopide lumbal bölge vertebralarında herhangi bir malformasyon izlenmedi ancak 3. ve 4.lumbal segmentte omuriliğin çapında daralma tespit edildi. Omurilik çapının en dar kesiminden hazırlanan kesitlerde, mikroskopik olarak, kanalis sentralisin tamamen gözden silindiği izlendi. Ayrıca dorsal ve ventral funikuluslarda siringomiyelik kavitasyonlar şekillendiği belirlendi.

Holstein ırkı bir buzağıda Omurilikte kongenital segmental hipoplazi olgusu

A case of congenital segmental spinal hypoplasia was described in a 40-day-old Holstein calf. The calf was submitted to our clinic (Istanbul University, Faculty of Veterinary Medicine, Education and Research Hospital, Surgery Clinic) with the complaint of not being able to rise to feet after birth. After clinical and radiologic inspection an anomaly was detected in spinal cord at the level of 3rd and 4th lumbar vertebrae. As the prognosis of the animal deteriorates, the calf was euthanized and systemic necropsy of the animal was performed. There was no malformation at the vertebrae around lumbar region, but a constriction was found at the third and fourth lumbar region of the spinal cord in macroscopy. It was detected that the sections prepared from the narrowest part of the medulla spinalis revealed the entire disappearance of the canalis centralis, microscopically. Furthermore syringomyelic cavities with different dimensions were observed in dorsal and ventral funiculi.

PDF

___

1. Leipold HW, Hiraga T, Dennis SM: Congenital defects of the bovine central nervous system. Vet Clin North Am: Food Anim Pract, 9, 77-91, 1993.
2. Cho DY, Leopold HV: Spina bifida and spinal dysraphism in calves. Zentalbl Vetinamed Med A, 24, 680, 1977.
3. Hiraga T, Abe M: Anatomical observation of six calves affected with segmental aplasia of the spinal cord. Anat Rec, 219, 402-408, 1987.
4. Jubb KVF, Huxtable CR: Dysraphic states. In, Jubb KVF, Kennedy PC, Palmer N (Eds): Pathology of Domestic Animals. 4th ed., 272-276, Academic Press, Newyork, 1993.
5. Imai S, Moritomo Y: Segmental hypoplasia of the spinal cord in a japanese black calf. J Vet Med Sci, 71, 337-340, 2009.
6. Noden DM, Lahunta A: Limb Development. The Embriyology of Domestic Animals-Developmental Mechanisms and Malformations. pp.196-209 Williams&Wilkins, 428 East Preston Street Baltimore, 1985.
7. Jones CJ: Perosomus elumbis (vertebral agenesis and arthrogryposis) in a stillborn Holstein calf. Vet Pathol, 36, 64-70, 1999.
8. Madarame H, Azuma K, Nozuki H, Konno S: Perocormus associated with segmental aplasia of the cervical spinal cord in a Japanese Shorthorn calf. J Comp Pathol, 101, 225-230, 1989.
9. Gulbahar MY, Yuksel H, Soyguder Z, Ercin OF: Dicephalus, arnold- chiari malformation, spinal dysraphism and other associated anomalies in a newborn holstein calf. Turk J Vet Anim Sci, 29, 565-570, 2005.
10. Ohfuji S: Spinal dysraphism in a newborn Holstein-Friesian calf. Vet Pathol, 36, 607-609, 1999.
11. Scott RM, Wolpert SM, Barthoshesky LE, Zimbler S, Karlin L: Segmental spinal dysgenesis. Neurosurgery, 22, 739-744, 1988.
12. Tortori-Donati P, Fondelli MP, Rossi A, Raybaud CA, Cama A, Capra V: Segmental spinal dysgenesis: Neuroradiologic findings with clinical and embriyologic correlation. Am J Neuroradiol, 20, 445-456, 1999.
13. Samsar E, Akın F: Özel Cerrahi. pp.344-345, Medipres Matbaacılık Yayincilik Ltd. Şti. Malatya, 2006.
14. Firat I, Yildiz F, Ozsoy S: A case of congenital flexure of fetlock in a holstein calf. J Fac Vet Med Istanbul Univ, 31, 103-108, 2005.