Topiramate add-on for treatment of migraine-type headache cures alcohol dependence: a case report

Topiramate add-on for treatment of migraine-type headache cures alcohol dependence: a case report

Topiramate presents a broad-spectrum efficacy in the treatment of different psychiatric and neurological conditions, assuggested by findings from studies on addiction, epilepsy, and migraine headaches. Here, we present a patient with adiagnosis of alcohol dependence that was treated with topiramate for migraine headaches as an add-on treatment topsychiatric medications. Alcohol craving and consumption were significantly reduced. Additionally, the patient’s migrainesymptoms improved, without the appearance of side effects.

___

  • 1. Arbaizar B, Gomez-Acebo I, Llorca J. Efficacy of topiramate in bulimia nervosa and binge-eating disorder: a systematic review. Gen Hosp Psychiatry. 2008;30(5):471-5. [CrossRef]
  • 2. Johnson BA, Ait-Daoud N, Akhtar FZ, Javors MA. Use of oral topiramate to promote smoking abstinence among alcoholdependent smokers: a randomized controlled trial. Arch Intern Med. 2005;165(14):1600-5. [CrossRef]
  • 3. Jonhson BA, Rosenthal N, Capece JA, Wiegand F, Mao L, Beyers K, et al. Topiramate for treating alcohol dependence: a randomized controlled trial. JAMA. 2007;298(14):1641-51. [CrossRef]
  • 4. Arbaizar B, Dierssen-Sotos T, Gomez-Acebo I, Llorca J. Topiramate in the treatment of alcohol dependence: a meta-analysis. Actas Esp Psiquiatr. 2010;38(1):8-12.
  • 5. Angehagen M, Ronnback L, Hansson E, Ben-Menachem E. Topiramate reduces AMPA-induced Ca(2+) transients and inhibits Glu R1 subunit phosphorylation in astrocytes from primary cultures. J Neurochem. 2005;94(4):1124-30. [CrossRef]
  • 6. White HS, Brown SD, Woodhead JH, Skeen GA, Wolf HH. Topiramate modulates GABA evoked currents in murine cortical neurons by a nonbenzodiazepine mechanism. Epilepsia. 2000;41(Suppl.1):17-20. [CrossRef]
  • 7. Weiss F, Porrino LJ. Behavioral neurobiology of alcohol addiction: recent advances and challenges. J Neurosci. 2002;22(9):3332-7.
  • 8. Johnson BA, Ait-Daoud N, Akhtar FM, Ma JZ. Oral topiramate reduces the consequences of drinking and improves the quality of life of alcohol-dependent individuals: a randomized controlled trial. Arch Gen Psychiatry 2004;61(9):905-12. [CrossRef]
  • 9. De Sousa AA, De Sousa, JA, Kapoor H. An open randomized trial comparing disulfiram and topiramate in the treatment of alcohol dependence. J Subst Abuse Treat. 2008;34(4):460-3. [CrossRef]
Journal of Mood Disorders-Cover
  • ISSN: 2146-1473
  • Başlangıç: 2011
  • Yayıncı: Psikofarmakoloji Derneği adına Mesut Çetin
Sayıdaki Diğer Makaleler

Schneider belirtileri ve DSM 5: ilişkili iki olgu sunumu

Kemal SAYAR, Ömer YANARTAŞ, Serhat ERGÜN, Erdoğdu AKÇA, Nurşin HİCRİ, Süha Can GÜRSOY

Assessment of treatment adherence in patients with bipolar disorder

Mehmet Emin DEMİRKOL, Lut TAMAM, Nurgul OZPOYRAZ, Mahmut GURBUZ, Mahmut Onur KARAYTUG, Necla KESKİN

Stress lived before conception alters the maturation of the offspring

Sabri BENKERMİCHE, Meriem HALOUİ, Amina DJOUİNİ, Fatiha BOUOUZA, Abdelkrim TAHRAOUİ

Topiramate add-on for treatment of migraine-type headache cures alcohol dependence: a case report

Aysun KALENDEROGLU, Murat Eren OZEN, Oguzhan Bekir EGİLMEZ, Mehmet Hamdi ORUM

Çocuk psikiyatri polikliniğine başvuran zihinsel engelli hastaların başvuru şikayetleri ve komorbid tanıları

Hatice ALTUN, Feyza Hatice SEVGEN, Asiye ARICI

Çocuk ve ergen psikiyatrisi polikliniğine başvuran 0-5 yaş arası çocukların başvuru şikayetleri ve psikiyatrik tanıları

Hatice ALTUN, Feyza Hatice SEVGEN

Kendilik algısı ve saldırganlık arasındaki ilişki: Yalnızlığın aracı rolü

Hatice ODACI, Çiğdem ÇELİK BERBER

Decrease in serum prolactin levels after long-acting injectable aripiprazole treatment: a case report

Orkun AYDİN, Pınar Unal AYDIN

Kariyer uyumluluğunun bireysel yönü: Kişilik özellikleri ve duygulanım açısından incelenmesi

Ali ERYILMAZ, Ahmet KARA

The effect of chlorpromazine on body temperature; three intensive care unit cases and a single outcome

Bulent Devrim AKCAY, Omur ILBAN