Sevgi KELEŞ, Cevdet ÖZDEMİR, Nerin Nadir BAHÇECİLER, İşıl Berat BARLAN

Periyodik Ateş Sendromları

Çocukluk çağında ateş etyolojisinin tam olarak aydınlatılamadığı durumlarda ‘periyodik ateş sendromları’ düşünülmelidir.PFAPA sendromu, Hiper IgD sendromu, Tümör nekroz faktörü ile ilişkili periyodik sendrom TRAPS , Ailesel soğuk ürtikeri, Muckle-Wells sendromu, Ailevi Akdeniz Ateşi FMF ve Siklik Nötropeni bu sendromları oluşturmaktadır. Bu hastalıklarotoimmun etyoloji veya infeksiyon olmadan sistemik inflamasyon ataklarıyla karakterizedir. Tekrarlayan ateş atakları olanbir çocukla karşılaşan hekimlerin bu hastalıklara özgü bazı ipuçlarından yararlanarak tanı koymaları mümkündür. Kliniktablo oldukça iyi tanımlanmasına karşın hastalığa özgü laboratuvar bulgularının olmayışı tanıyı güçleştirmektedir. Bu yazıda bu hastalıklardan bahsedilmektedir

Anahtar Kelimeler:

Ailesel soğuk ürtikeri, ailevi akdeniz ateşi, hiperIgD, Muckle-Wells, siklik nötropeni, periyodik ateş, PFAPA, TRAPS

Periodic Fever Syndromes

When common infectious agents and other causes of fever such as neoplastic and rheumatologic diseases, immune deficiencies, various endocrinologic and metabolic disorders are differentiated, periodic fever syndromes must be brought inmind in recurrent fever attacks of childhood. Among periodic fever syndromes PFAPA, hyper-IgD syndrome, tumor necrosis factor receptor-associated periodic syndrome TRAPS , familial cold urticaria, Muckle-Wells syndromes, familial Mediterranean fever and cyclic neutropenia are well described. Although clinical findings are clear enough , as there is no specific test for these diseases, it is sometimes hard to diagnose. Hereby, we rewieved these diseases which may cause recurrent fever attacks in children

Keywords:

Cyclic neutropenia, familial cold urticaria, familial mediterenean fever, hyperIgD, Muckle-Wells, periodic fever, PFAPA, TRAPS,

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