Berna AKTÜRK, Solmaz ÇELEBİ, Mustafa K. HACIMUSTAFAOĞLU

Aspergilloz

Aspergillus türleri, 900 den fazla türü olan, tüm dünyada çürüyen materyal üzerinde sık ve yaygın olarak bulunan saprofit bir mantar ailesidir. İnsanlarda invaziv hastalık, invaziv olmayan hastalık ve aşırı duyarlılık sendromu olmak üzere üçfarklı hastalık grubuna neden olurlar. Aspergillus türleri özellikle bağışıklık sisteminde sorun olan hastalarda ciddi enfeksiyonlara neden olan ve bağışıklık sistemini baskılayan ilaçların ve antibiyotiklerin yaygın olarak kullanılması ile önemi giderek artan enfeksiyonlara sebep olan mantarlardır. Bu yazıda özellikle invazif aspergilloz enfeksiyonunun patolojisi, patofizyolojisi, klinik tabloları, tanı ve tedavisi anlatılmaktadır

Anahtar Kelimeler:

Aspergillozis, mantar, tedavi

Aspergillosis

Ubiquitous saprophytic molds, Aspergillus species are common on decaying material throughout the world. More than900 species are included in the genus Aspergillus. Among human beings 3 different clinical presentations including invasive disease, non-invasive disease and hypersensitivity reactions may occur due to Aspergillus species. Especially immunosuppressed patients are under the risk of invasive aspergillosis, and in consequence of extensive use of immunosuppresormedications and broad spectrum use of antibiotics, Aspergillus species gain importance among infectious diseases. In thisarticle, pathology, pathophysiology, clinical pictures, diagnosis and treatment of invasive aspergillosis are overwieved

Keywords:

Aspergillosis, fungus, treatment,

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