Tolga Altuğ ŞEN, Reşit KÖKEN, Tevfik DEMİR, Hamide MELEK, Adnan NARCI

Afyonkarahisar Merkezindeki Sağlıklı Çocuklarda Spot İdrar Kalsiyum/Kreatinin Oranlarıyla ve 24 Saatlik İdrarla Kalsiyum Atılımının Değerlendirilmesi

Amaç: Hiperkalsiüri çocuklarda çoğunlukla asemptomatik seyreden önemli bir sağlık sorunudur. Hiperkalsiüri çocuklardaki böbrek taşları için başlıca risk faktörlerindendir. Bu çalışmada çocuklarda ve özellikle bebeklerde 24 saatlik idrar toplanmasındaki güçlüklerden dolayı idrarla kalsiyum atılımının saptanması için spot idrar örneklerinde kalsiyum/kreatinin oranlarının değerlendirilmesini amaçladık. Gereç ve Yöntem: Çalışmamız için şubat 2001-Ocak 2003 tarihleri arasında, değişik nedenlerle polikliniğimize başvurmuş olan yaşları 4 ayla 16 yaş arasında değişen 1027 çocuk 516 kız, 511 erkek seçilmiştir. Bütün çocukların sabah ikinci idrar örnekleri alınmıştır. Kalsiyum/kreatinin oranı yüksek bulunan çocuklar arasından 24 saatlik idrar toplayabilecek durumda olanları için 24 saatlik idrar örnekleri toplamaları istenmiştir. Bulgular: Kız çocuklar için ortalama kalsiyum/kreatinin oranı 0,093 ±0,077, S.D. , erkek çocuklar içinse 0,104 ±0,075, S.D. olarak bulunmuş olup, erkeklerdeki oran anlamlı olarak yüksektir p=0,002 . Yaşları 4-12 ay arasında olan bebeler için kalsiyum/kreatinin oranı ortalama 0,203 ±0,121, S.D. , 13 ay- 6 yaş arasındaki küçük çocuklar için 0,133 ±0,081,S.D. , 7-11 yaş arasında büyük çocuklar için 0,095 ±0,071,S.D. ve 12-16 yaş arasındaki adölesanlar için 0,061 ±0,062, S.D. olarak tespit edilmiş olup, aradaki farklılıklar anlamlı bulunmutur p

Anahtar Kelimeler:

Spot idrar kalsiyum/kreatinin oranı, 24 saatlik idrar kalsiyum atılımı, vücut-kitle indeksi, sağlıklı çocuklar

Evaluation of Spot Urine Calcium/Creatinine Ratio and 24-Hour Urinary Calcium Excretion in Healthy Children Living in Afyonkarahisar

Aim: Hypercalciuria is an important health problem especially during childhood. Hypercalciuria is usually asymptomatic, but it is a common risk factor in the formation of renal stones. In this study we evaluated urinary calcium excretion of infants and children. It is difficult to collect 24-hour urine samples especially for little children. Due to this difficulty random urine samples were evaluated and hypercalciuria was measured as the calcium / creatinine concentration ratio in the second non-fasting urine samples. Material and Methods: We selected 1027 children, 516 healthy girls and 511 healthy boys, aged 4 months to 16 years who were admitted to our clinic due to various simple complaints between February 2001 and January 2003. Each of them gave random urine sample for the assessment of calcium and creatinine excretion. When the calcium/creatinine ratio in random urine sample was high, 24-hour urine calcium collection for the calcium excretion was ordered. Results: The mean urinary calcium/creatinine ratio in girls was 0,093 ±0,077, S.D. ; in boys it was 0,104 ±0,075, S.D. ; boys had higher urine calcium/creatinine ratios than girls p=0,002 in all age groups. Infants to 4 months- 12 months old mean 0,203±0,121, S.D. , and small children, 13 months to 6 years old had higher urine calcium/creatinine ratios mean 0,133±0,081,S.D. than older children 7 - 11 years old, mean 0,095±0,071,S.D. and adolescents 12-16 years old, mean 0,061±0,062, S.D. p

Keywords:

Urinary calcium/creatinine ratio, 24-hour urine calcium excretion, body mass index, healthy children,

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