Serum crp düzeylerinin lomber dejeneratif hastalık şiddetini belirlemedeki rolü

Amaç: Bu çalışmanın amacı polikliniğe başvuran kronik bel ağrılı hastaların serum CRP düzeyi ile hastalık derecesinin arasında ilişki olup olmadığını belirlemektir. Gereç ve Yöntem: Veriler hastane veri sisteminden retrospektif olarak elde edilerek yapılmıştır, Beyin ve Sinir cerrahisi polikliniğine başvuran 54 hastanın serum CRP düzeyleri taranarak elde edilmiştir. Hastalar medikal tedavi alan grup (n=14), spinal stenoz tanısı ile tek taraflı yaklaşımla bilateral mikro dekompresyon yapılan grup (n=19) ve mikro diskektomi yapılan grup (n=21) olmak üzere üç gruba ayrılmıştır. Üç grup hastanın serum CRP düzeyleri arasında farklılık olup olmadığı Kruskal Wallis yöntemi ile karşılaştırılmış ve hangi gruplar arasında istatistiksel farklılık olup olmadığını belirlemek için One-Way Post Hoc testi uygulanmıştır. Bulgular: Bu çalışmadayaş ortalaması 40 olan 54 hasta (23’ ü erkek 31’i kadın) incelenmiştir. CRP değerlerini Kruskal Wallis testi ile karşılaştırdığımızda hem medikal tedavi uygulanan hasta grubu ile mikrodiskektomi yapılan hasta grubu hem de medikal tedavi uygulanan hasta grubu ile unilateral yöntemle bilateral dekompresyon yapılan hasta grubu arasında farklılık olduğu görüldü (p=0.05). One-Way Post Hoc testi ile medikal tedavi verilen bel ağrılı hastalar ile cerrahi uygulanan gruplar arasında anlamlı istatistiksel farklılık olduğu görüldü (p

The role of serum crp level to determine the severity of lumbar degenerative disc disease

Objective: The aim of this study was to determine whether there was a relationship between serum CRP level and disease grade in patients with chronic low back pain who applied to neurosurgery clinic. Material and Methods: The data were obtained retrospectively from hospital data system. The serum CRP levels of 54 patients who were admitted to the neurosurgery clinic were obtained. The patients were divided into three groups: Received medical treatment group (n = 14), patients with spinal stenosis peformed bilaterally decompression via unilateral aprroach(n = 19), and microdiscectomygroup (n = 21). CRP levels were compared if there was any statistical difference between the groupsbyKruskal-Wallis method and applied the One-Way Post Hoc test to determine the statistical difference between the groups. Results: 54 patients (23 female and 31 male), whose average age was 40, was studied in this article. According to the CRP values compared with the Kruskal Wallis test, statistical difference was observed both between the medically treated group and microdiscectomy group and medically treated group and underwent bilateral decompression by unilateral laminectomy groups (p= 0.05). A significant statistical difference was found between the patients treated with medically and the patients who had surgical treatment bythe OneWay Post Hoc test (p< 0.05). Conclusion: This study revealed that serum CRP levels of patients with chronic low back pain were found to be high in patients who underwent surgery and patients with chronic low back pain, especially those with high CRP levels, could be candidates for surgery. Because of CRP is an easy and inexpensive method, it can be used as a laboratory marker to determine the candidate patients in patients with chronic low back pain.

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