Atilla EROL, Hilal GÜNAL, Eser ŞAVKILIOĞLU

Rijit bronkoskopide kullanılan mivakuryum ile süksinilkolinin nöromüsküler ve hemodinamik etkiler açısından karşılaştırılması

Amaç: Çalışmamızda rijit bronkoskopilerde süksinilkolin ile yeni bir kısa etkili nondepolarizan kas gevşetici ajan olan mivakuryumu entübasyon kalitesi, etki süresi ve hemodinami açısından karşılaştırmayı amaçladık. Yöntem: Araştırmamız genel anestezi altında rijit bronkoskopi planlanan ASA l-ll, yaşları 18-70 arasında değişen 30 hasta üzerinde yapıldı. Hastalar mivakuryum ve süksinilkolin verilen grup olmak üzere tesadüfi olarak 15'er kişilik iki gruba ayrıldı. Bulgular: Gruplar arasında onset time (OT) ve entübasyon anındaki nöromüsküler blok (EANMB) % açısından önemli fark bulundu. Maksimum nöromüsküler blok (MNMB)% ve entübasyon skoru açısından anlamlı fark bulunmadı. Sonuç: Süksinilkolin ve antikolinesteraziara ait ciddi yan etkiler göz önüne alındığında mivakuryumun kısa cerrahi işlemlerde bir alternatif olduğu sonucuna varıldı.

Anahtar Kelimeler:

Anestezi, genel, Bronkoskopi, Süksinilkolin, Kolinesteraz inhibitörleri

Comparison of the effects of mivacurium and succinylcholine, used for rigid bronchoscopy, on neuromuscular block and hemodynamics

Aim: in this study, we aimed to compare the effects of mivacurium, is a new short-acting non:depolarizing muscular relaxant, with succinylcholine on neuromuscular block and homodynamic during rigid bronchoscopy. Methods: The study group consisted of thirty adults, ASA physical status l or II; aged 18-70 years and scheduled for rigid bronchoscopy under general anesthesia. Patients were assigned randomly to receive either mivacurium (n=15) or succinylcholine (n=15). Results: There was a significant difference in the onset time (OT) and neuromuscular block during intubation % between two groups. There were no statistically significant differences in maximum neuromuscular block % and intubation score. Conclusion: We concluded that, if severe side effects of succinylcholine or anticholinesterase are considered, mivacurium might be an altemative during short surgical procedures

Keywords:

Anesthesia, General, Bronchoscopy, Succinylcholine, Cholinesterase Inhibitors,

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