Hüseyin DEMİRCİ, Bilge CEYDİLEK, Reyhan BAYRAK, Halise ÇINAR YAVUZ

Warthin Benzeri Papiller Tiroid Karsinomu: Olgu Sunumu

Warthin benzeri papiller tiroid karsinomu, nadir görülen bir tiroid papiller karsinom varyantıdır. Tümör ismini, tükrük bezinin Warthin tümörüne morfolojik olarak benzerliğinden almaktadır. Beş yıldır nodüler guatr tanısıyla takip edilmiş olan 39 yaşındaki kadın hastanın tiroid sağ lobunda saptanan nodülden yapılan ince iğne aspirasyon biyopsisi papiller tiroid karsinomu ile uyumlu geldi. Hastaya bilateral total tiroidektomi yapıldı. Mikroskopik olarak belirgin papiller yapıları döşeyen şeffaf nükleuslu, bazılarında belirgin nükleusta geniş yer kaplayan sitoplazmik inklüzyonlar içeren atipik hücrelerden oluşan tümör izlendi. Papiller yapıların ortasında yoğun lenfositik hücreler görüldü. Warthin benzeri tiroid tümörlerinin prognozu ile ilgili sınırlı sayıda bilgi bulunmakla birlikte literatürdeki bilgiler genel olarak iyi prognoza sahip olduğunu göstermektedir.

Warthin Like Papillary Carcinoma of the Thyroid: A Case Report

Warthin-like pappillary thyroid carcinoma is a rarely seen variant of thyroid papillary carcinoma. The name of the tumor originates from salivary gland's resemblance to Warthin tumor morphologically. A 39-year old female patient whose nodular goiter had been followed for 5 years applied to our clinic for the swelling on her neck. The fine-needle aspiration biopsy performed on the nodule identified in the patient's right lobe of thyroid revealed papillary thyroid carcinoma. The patient underwent bilateral total thyroidectomy. Tumor cells was monitored with clear nuclei, and nuclear pseudoinclusions. Intense lymphocytic cells in the middle of the papillary structures were identified. Notwithstanding that there is a limited number of knowledge about the prognosis of the warthin-like thyroid tumors, the literature, in general, shows that they have mostly good prognosis.

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