Hüseyin EKEN, İsmail ZİHNİ, Oktay KARAKÖSE, Hüseyin PÜLAT, Kazım ÇAĞLAR, Hasan EROĞLU

Mide Kanserli Olguların Geriye Dönük İncelenmesi

Amaç: Mide kanseri Avrupa’da kadınlarda ve erkeklerde görülme sıklığıaçısından beşinci sırada yer almaktadır. Erkek kadın oranı ise 1.6:1 olarakbelirlenmiştir. Mide kanseri, kansere bağlı ölümlerde ülkemizde erkeklerdeikinci, kadınlarda ise üçüncü sırada yer almaktadır. Mide kanserinin prognozugenellikle kötüdür. Bunun sebebi de tanıda gecikme ve tanı konan olgularınileri evrede olmasıdır.Gereç ve Yöntemler: Süleyman Demirel Üniversitesi Tıp Fakültesi GenelCerrahi Anabilim Dalı 1995 -2009 yılları arasında mide kanseri tanısı ilecerrahi işlem yapılan 204 olgu geriye dönük olarak incelendi. Bu olgulardan131’ine küratif cerrahi rezeksiyon yapıldığı belirlendi. Olguların %80’i lokalileri evre olgulardı (evre IIIa, IIIb ve IV). Olguların yaş, cinsiyet, başvurusemptomları, tümör lokalizasyonu, T, N, M, evre, tümör diferansiyasyonu,histolojik tipleri, tümör çapı, vasküler ve perinöral invazyon varlığı, yapılancerrahi işlem, rezeksiyon tipi, diseksiyon tipi, diseke edilen toplam lenf nodusayısı, metastatik lenf nodu varlığı, metastatik lenf nodu sayısı ve toplam lenfnodu sayısına oranı, komplikasyonlar, cerrahi mortalite, adjuvan kemoterapi,adjuvan radyoterapi ve diğer adjuvan tedavileri ve sağkalım süreleribelirlendi. Bu verilerin sağkalım üzerine etkileri lojistik regresyon analizi iledeğerlendirildi. Sağkalım açısından 3 ve 5 yıllık sağkalım eğrileri Kaplan-Meieryöntemiyle çıkarıldıBulgular: Küratif rezeksiyon ve diseksiyon yapılan 131 olguda morbidite%15.2, mortalite ise %7.6 idi. Evre ve metastatik lenf nodlarının toplam lenfnodu sayısına oranı sağkalım üzerinde en önemli faktörler olarak bulundu(p

Objective: Gastric cancer is the fifth most commen neoplasm in terms of incidence in men and women in Europa. Male to female ratio was determined as 1.6:1. Gastric cancer is the second most commen neoplasm in men and third most commen neoplasm in female in deaths due to cancer in our country. Prognosis of gastric cancer is generally reserved. The low survival rate is due to the delay in diagnosis, most cases being diagnosed in an advanced stage. Material and Methods: Between 1995 and 2009, 204 gastric cancer patients were retrospectively evaluated who was treated surgically in Faculty of Medicine, Suleyman Demirel University. It was observed that tumors of the 131 patients were curatively resected. The great portion (80%) of these patients were in locally advanced stages (stage IIIa, IIIb and IV). Age, gender, symptoms, tumor localisation, T, N, M, stage, tumor differantiation, histologic type, occurence of vascular and perineural invasion, surgery type, resection type, dissection type, count of dissected lymph nodes, metastatic lymph nodes, ratio of metastatic lymph nodes, complications, morbidity and mortality, adjuvant chemotherapy schedules, adjuvant radiotherapy and other adjuvant therapies, and surviaval of these patients were analyzed. For detecting the effects of these factors upon survival, logictic regression analysis was performed. Survival times were analyzed with Kaplan-Meier method. Results: It was seen that surgical morbidity was 15.2%, and mortality was 7.6% in curatively resected 131 patients. Stage and the ratio of metastatic lymph nodes were evaluated as significantly important in survival (p

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