Böbreğin toplayıcı kanal kanseri: Literatürün klinikopatolojik bulgularımızla gözden geçirilmesi

Böbreğin Toplayıcı Kanal Karsinomu (TKK) distal toplayıcı kanallardan köken alan ender bir böbrek hücreli kanser histolojik alt tipidir, lokal agresif ve uzak yayılım ile ilişkilidir. Hastalar genellikle ileri evrede tanı alırlar, cerrahi tedavi ve veya kemo/immünoterapi kür sağlamaya yeterli değildir. TKKli hastaların sağkalım süresi sıklıkla kısadır. Dünya genelinde az sayıda olgu mevcuttur ve kabul edilmiş bir tedavi protokolü mevcut değildir. Klinik semptomlar ve radyolojik bulgular diğer histolojik alt tiplerle benzerdir. (Gazi Med J 2012; 23: 25-8)

Collecting duct carcinoma of the kidney: Review of the literature with our clinicopathological findings

Collecting duct carcinoma (CDC) is a rare histological type of renal cell carcinoma, which originates from the distal collecting ducts and is associated with aggressive regional and distant spread. Patients are generally diagnosed with advanced disease and the standard treatment of surgery with or without immuno/chemotherapy is not enough to effect a cure. Patients with CDC usually have a short survival time. Case reports of CDC are very rare, so there is no generally accepted therapy protocol. The clinical symptoms and radiologic findings are similar for all subtypes of renal cell carcinoma. (Gazi Med J 2012; 23: 25-8)

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  • Turunç T, Bolat F, Eğilmez T, Özkardeş S. Böbreğin Toplayıcı Kanal Kanseri: İki Olgu Sunumu Türk Üroloji Dergisi 2005; 31: 280-3.
  • Chao D, Zisman A, Pantuck AJ, Gitlitz BJ, Freedland SJ, Said JW, et al. Collecting Duct Renal Cell Carcinoma: Clinical Study Of A Rare Tumor. J. Urol 2002; 167: 71-4.
  • Kennedy SM, Merino MJ, Linehan WM, Roberts JR, Robertson CN, Neumann RD. Collecting duct carcinoma of the kidney. Hum Pathol 1990; 21: 449.
  • Karakiewicz PI, Trinh QD, Rioux-Leclercq N, de la Taille A, Novara G, To stain J, et al. Collecting Duct Renal Cell Carcinoma: A Matched Analysis of 41 Cases. Eur. Urol 2007; 52: 1140-6.
  • Tokuda N, Naito S, Matsuzaki O, Nagashima Y, Ozono S, Igarashi T. Japanese Society of Renal Cancer. Collecting Duct (Bellini Duct) Renal Cell Carcinoma: A Nationwide Survey in Japan. J. of Urol. 2006; 176: 40-3.
  • Wright JL, Risk MC, Hotaling J, Lin DW. Effect of Collecting Duct Histology on Renal Cell Cancer Outcome. J. Urol 2009; 182: 2595-600.
  • Sene AP, Hunt L, McMahon RF, Carroll RN. Renal carcinoma in patients undergoing nephrectomy: analysis of survival and prognostic factors. Br J Urol 1992; 70: 125-34.
  • Dimopoulos MA, Logothetis CJ, Markowitz A, Sella A, Amato R, Ro J. Collecting duct carcinoma of the kidney. Br J Urol 1993; 71: 388-91.
  • Igarashi T, Murakami S, Isaka S, Okano T, Shimazaki J, Matsuzaki O. Serum immunosuppressive acidic protein as a tumor marker for renal cell carcinoma. Eur Urol 1991; 19: 332-5.
  • Srigley JR, Eble JN. Collecting duct carcinoma of the kidney. Semin Diagn Pathol 1998; 15: 54-67.
  • Kirkali Z, Celebi I, Akan G, Yörükoğlu K. Bellini duct (collecting duct) carcinoma of the kidney. Urology 1996; 47: 921-3.
Gazi Medical Journal-Cover
  • Yayın Aralığı: Yılda 4 Sayı
  • Yayıncı: Gazi Üniversitesi Tıp Fakültesi