F. Güçlü PINARLI, Aynur OĞUZ, Meltem PELİT, Gürsel BİBEROĞLU, Alev HASANOĞLU, Ceyda KARADENİZ

Amino acid profiles in pediatric solid tumors

Bu çalışmada solid tümörlerde plazma amino asit düzeyleri saptanmış ve malign hastalıkların yol açabileceği karakteristik değişiklikler ve beslenme durumu ile olan ilişkileri araştırılmıştır. Metod: Yaşları 8 ay ile 13 yaş arasında değişen (ortalama 6.78 ± 3.76) 34 yeni tanı almış kanser hastası (19 Non Hodgkin Lenfoma, 10 Hodgkin hastalığı, 5 Wilms tümörü) ve yaşları 3 ay ile 14 yaş arasında değişen (ortalama 4.62 ± 4.71) 15 sağlıklı çocukta plazma amino asit düzey ölçümü yapılmıştır. Sonuçlar: Aspartat ve glutamat düzeyleri Wilms tümörlü hastalarda yüksek bulunmuştur (p

Pediyatrik solid tümörlerde amino asid profilleri

In the current study, plasma amino acid levels were determined in children with solitary tumors in order to assess whether malignant disease produces characteristic changes and whether changes are attributable to the nutritional status of patients. Methods: Thirty four patients (24 boys-10 girls) aged between eight months and 13 years whose tumors had recently been diagnosed and who had not previously been treated were included in the study. The diagnoses were as follows: 19 Non-Hodgkin's lymphomas , 10 Hodgkin's disease (HD), 5 Wilms' tumors. Fifteen healthy children served as controls. Results: Aspartate and glutamate levels were found to be increased in patients with Wilms' tumor (p

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