Erythrocyte superoxide dismutase and catalase activities in people chronically exposed to pesticides

Bu çalışmada tarım alanlarına yakın yerleşim bölgelerinde yaşayan ve pestisitlerin kronik etkisine maruz kalan yöre halkında eritrosit süperoksit dismutaz ve katalaz aktivitelerinin incelenmesi amaçlanmıştır. Gereç ve Yöntem: Mersin ve çevresi tarım alanlarının yakınındaki yerleşim bölgelerinde yaşayan (15.03^.2.25 yıl ) ve pestisitlerin kronik etkisine maruz kalan kişilerden (n-50) kan örnekleri alınmış ve bu örneklerden elde edilen eritrositlerde süperoksit dismutaz (SOD) ve katalaz (ÇAT) aktiviteleri spektrofotometrik olarak ölçülmüştür. Aynı ölçümler pestisitlere herhangi bir şekilde maruz kalmayan kişilerde (n=30) de yapılmıştır. Bulgular: Yöre halkında eritrosit SOD aktiviteleri kontrol grubuna oranla daha yüksek bulunurken (p

Pestisitlerin jkronik etkisine maruz kalan yöre halkında eritrosit süperoksit dismutaz ve katalaz aktiviteleri

Purpose: In this study, we aimed to investigate the effects of chronic exposure to pesticides on erythrocyte Superoxide dismutase (SOD) and catalase (CAT) activities in residents who have lived near agricultural areas. Methods: Blood samples were taken from residents (n=50) who had long-term exposure to pesticides (15.03^2.25 years) in Mersin and erythrocyte SOD and CAT activities were measured using spectrophotometric techniques. These antioxidant system enzymes were also evaulated in persons not exposed to pesticides in any known way (n=30). Results: Erythrocyte SOD levels were significantly higher (p'-0.001) but erythrocyte catalase activities were significantly lower (p

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