Şevki SERT, A. Ziya ANADOL, Metin ONARAN, Musa BALİ

The first 70 renal transpalnts at Gazi University

Son dönem böbrek hastalığı için tüm dünyada ve 1975"den bu yana Türkiye'de de tercih edilen tedavi seçeneği böbrek trasplantasyonudur. Çalışmamızda Gazi Üniversitesi Tıp Fakültesi'nde yapılan böbrek trasplantasyonlan incelenmiştir. Metod: Eylül 1996 ile Mart 2001 tarihleri arasında hastanemizde 70 böbrek trasplantasyonu gerçekleştirilmiştir. 57 transplantasyon canlı donörden, 13 transplantasyon kadavra donörden yapılmıştır. Hastalar üçlü immünsüpresif tedavi (Siklosporin-A veya Takrolimus, Azotioprin veya Mikofenolat Mofetil ve prednizolon) almışlardır. Rejeksiyon atakları bolus metilprednizolon ve/veya poliklonal veya monoklonal antikorlar ile tedavi edilmiştir. Bulgular: l ve 3 yıllık greft yaşam süreleri iki haplotip uyumlu hastalar için sırasıyla %100 ve %94,4, bir haplotip uyumlulurda %92,3 ve % 84,6, kadavra böbreklerde ise %69,2 ve % 61,6 bulunmuştur. Sonuç: Tüm gruplarda hasta ve greft yaşam süreleri kabul edilebilir düzeydedir ve Gazi Üniversitesi'nde böbrek trasplantasyonu başarılı sonuçlarla devam etmektedir.

Gazi Üniversitesi'nde yapılan ilk 70 böbrek transplantasyonu

Kidney transplantation is accepted as the treatment of choice for end stage renal disease all over the world and also in Turkey since 1975. We reviewed our results in Gazi University. Methods: Seventy patients underwent kidney transplantation at Gazi University, School of Medicine, Transplantation Center between September 1996 and March 2001. Fifty-seven of these were from living relatives and 13 from cadaveric donors. Patients received triple drug immunosuppressive regimen (Cyclosporine-A or Tacrolimus, Azathioprine or Mycophenolate mofelil and Prednisolone). Rejection episodes were treated with bolus methylprednisolone and/or polyclonal or monoclonal antibodies. Results: We have found one and three year graft survival rates were 100% and 94,4% m the two haplotype group; 92,3 % and 84,6% in the one haplotype group; 69,2% and 61,6% in the cadaveric group, respectively. Conclusion: Patient and graft survivals are quite reasonable in all groups and kidney transplantation program is successfully continuing with promising results at Gazi University.

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