Mine ERİŞİR, Mehtap ÖZÇELİK, Osman GÜLER, Murat BAYKARA

Tüm Vücut Radyasyonu Uygulanan Ratlarda Oksidatif Hasar Üzerine Propolisin Etkisi

Radyasyona bağlı oksidatif hasara karşı propolisin antioksidan ve radyoprotektif etkileri araştırıldı. Yirmi bir rat 3 gruba bölündü; 1. grup kontrol grubu; 2. grup radyasyon grubu; serum fizyolojik (i.p.)/3 gün + 9 Gy gamma radyasyon; 3. grup radyasyon + propolis grubu; propolis (i.p. 100 mg/kg CA)/3 gün + 9 Gy gamma radyasyon uygulandı. Radyasyon sonucu, ratların karaciğer, böbrek ve beyin dokularının malondialdehit (MDA) düzeylerinde anlamlı bir artış tespit edildi (P

The Effect of Propolis on Oxidative Damage Induced by Whole Body Irradiation in Rat

The antioxidant and radioprotective effects of propolis against ionizing radiation induced oxidativedamage were investigated. Twenty one rats were divided in to 3 groups; 1 st group was the controlgroup; 2nd group was the irradiation group, physiological saline (i.p.)/ 3 days + 9 Gy gammairradiation; 3rd group was irradiation + Propolis group, propolis (i.p. 100 mg / kg BW) / 3 days + 9Gy gamma irradiation. As a result of irradiation, a significant increase was determined inmalondialdehyde (MDA) levels of liver, kidney, and brain tissues of the rats (P

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