Ali Osman ÇERİBAŞI, Mustafa SÖNMEZ, Abdurrauf YÜCE, Gaffari TÜRK, Ahmet KAVAKLI, Mehmet Cengiz HAN, Ömer ATALAR

Diyabet, yara iyileşmesi ve sperm kalitesi üzerine akupunkturun önemi

Akupunktur; fonksiyonel, geriye dönüşümlü hastalık ya da bozuklukların tanısı ve/veya sağaltımı için deride kendiliğinden bulunan basınca hassas ve önceden yerleri kesin olarak belirlenmiş bazı anatomik nokta ya da noktaların iğnelenmesidir. Dünyada artan ilgi ivmesinin aksine, ülkemizde akupunktur önemini yitirmese de, projeleri çok fazla destek bulmayan, bu sebeple araştırmacıların da fazla irdelemediği bir alan olarak varlığını sürdürmektedir. Pahalı teknik donanımlar, nitelikli personeller ve uzun araştırma süreçleri istemeyen akupunktur tedavi yöntemleri; en kısa zamanda, en ucuz maliyetle, en az yan etki ve en kolay uygulama olanakları ile hem bilime hem de ekonomiye önemli katkılar sağlayabilme imkânlarına sahiptir. Yapılan literatür taramalarında; yara iyileşmelerindeki gecikmeler ve düşük sperm kalitesi üzerine akupunktur uygulamalarının olumlu sonuçlar verdiğine yönelik çok sayıda çalışma tespit edilmiş; ancak derlemeye konu olan diyabet kaynaklı yara iyileşmeleri ve sperm kalitesi üzerine akupunktur uygulamalarının iyileştirici etkisiyle ilgili ayrıntılı bir derlemeye rastlanılmamıştır. Bu derlemenin alanındaki bilgi birikimine katkı sağlayacağı düşünülmektedir.

The importance of acupuncture on diabetes, wound healing and sperm quality

Acupuncture is needling the anatomical point(s), which are self-contained pressure-sensitive and defined in advance as a definite, in skin for diagnosis and/or treatment of functional, reversible disease or disorders. Contrary to the growing momentum of interest in the world, though it does not lose its importance in our country, acupuncture is maintained its existence as a field that projects related to acupuncture find no much support, so the researchers did not investigate too much. Acupuncture treatment methods that do not require expensive technical equipment, qualified personnel and the long process of research, have many oppurtunities to provide major contributions to science and economics with the cheapest cost, a minimum side effects and easy application. In the structured literure review; many scientific studies dealing with improving effects of acupuncture on delay in wound healing and low sperm quality was determined, but it has not been observed any scientifically detailed review related to improving effects of acupuncture on diabetes- induced oxidative stress, delayed wound healing and low sperm quality. It is thought that this review will provide an important contribution in its field.

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1. Çaptuğ Ö, Bilgili H. Köpeklerde akupunktur. Bölüm I: Akupunkturun tarihçesi, etki mekanizması ve akupunktur yöntemleri. Veteriner Cerrahi Dergisi 2005;11: 67-76.
2. Karamehmetoğlu ŞS. “Bilimsel verilerin ışığı altında akupunktur ve fiziksel tıp ile rehabilitasyon”. www.tamtip.com/kategori.php/13.04.2005.
3. Çevik C. Medikal Akupunktur. Ankara: Promat A.Ş., 2001.
4. Brunner F. Akupunktur für Tierarzte Akupunktur der Kleintiere. Schordorf: WBV Biologisch-Medizinische Verlagsgesellschaft mbH& Co KG, 1980.
5. Haltrecht H. Veterinary acupuncture. Can Vet J 1999; 40: 401-403.
6. Mc Cauley L, Glinski MH. Acupuncture for veterinary rehabilitation. In: Millis DL, Lenine D, Taylor RA. (Editors). Canine Rehabilitation and Physical Theraphy. St. Louis, MO, USA: W.B. Saunders Co 2004: 337-354.
7. Jagger DH. History and concepts of veterinary acupuncture. In: Schoen AM. (Editor). Veterinary Acupuncture: Ancient Art to Modern Medicine. St Louis, MO, USA: Mosby-Year Book 1994: 5-18.
8. Bossut DFB, Stromberg MW, Malven PV. EA-induced analgesia in sheep: measurement of cutaneous pain thresholds and plasma concentrations of prolactin and β- endorphin immunoreactivity. Am J Vet Res 1986; 47: 669- 676.
9. Wang T, Zhang Q, Xue X, Yeung A. A systematic review of acupuncture and moxibustion treatment for chronic fatigue syndrome in China. Am J Chin Med 2008; 36: 1-24.
10. Janssens LA. Some aspects of small animal acupuncture. Belgian Vet Acup Soc Bull 1988; 176: 23- 41.
11. Altman S. An Introduction to Acupuncture for Animals. USA: Chan’s Corporation, 1984.
12. Kavaklı A. Akupunktur. Fırat Tıp Dergisi 2010; 15: 1-4.
13. Gülanber EG. Veteriner Hekimlikte Akupunktur ve Akupunktur Uygulamaları. Doktora Tezi, İstanbul: İstanbul Üniversitesi, Sağlık Bilimleri Enstitüsü, 1994.
14. Klide AM, Farnbach GC, Gallagher SM. Acupuncture therapy for the treatment of intractable, idiopathic epilepsy in five dogs. Acupunct Electrother Res 1987; 12: 71-74.
15. Hunt TK. Basic principles of wound healing. J Trauma 1990; 30: S122-128.
16. Carrigo TJ, Melhrof AI, Cohen IK. Biology of wound healing. Surg Clin North Am 1984; 64: 721-733.
17. Whitney JD. Physiologic effects of tissue oxygenation on wound healing. Heart Lung 1985; 18: 466-474.
18. Ekmektzoglou KA, Zografos GC. A concomitant review of the effects of diabetes mellitus and hyperthyroidism in wound healing. World J Gastroenterol 2006; 12: 2721- 2729.
19. Suh DY, Hunt TK, Spencer EM. Insulin-like growth factor-1 reverses the impairment of wound healing induced by corticosteroids in rats. Endocrinology 1992; 131: 399-403.
20. Werner Breeden M, Hubrer G, Greenhalg DG, Longaker MT. Induction of keratinocyte growth factor is reduced and delayed during wound healing in the genetically diabetic mouse. J Invent Dermatol 1994; 103: 469-473.
21. Bhora FY, Dunkin BJ, Batzri S, Aly HM, Bass BL, Sisawy AN, et al. Effect of growth factors on cell proliferation and epithelization in human skin. J Surg Res 1995; 59: 236- 244.
22. Peacock EE. Healing and control of healing. World J Surg 1980; 4: 269-270.
23. Davis RH, Donato JJ, Hartman GM, Haas RC. Anti- inflammatory and wound healing activity of a growth substance in Aloe vera. J Am Podiatr Med Assoc 1994; 84: 77-81.
24. Matera JM, Dagli MLZ, Pereira DB. The effect of soft-laser (diodes) radiation on wound healing in cats. Brazil J Vet Res Anim Sci 1994; 31: 43-48.
25. Houghton PE, Campbell KE. Choosing an adjunctive therapy for the treatment of chronic wounds. Ostomy Wound Manage 1999; 45: 43-52.
26. Zheng J, Wang S, Guo L. Promotion of wound healing with fibroblast growth factor in combined burn radiation injury. Chinese J Plastic Surg 1994; 10: 146-149.
27. Geronemus RG, Mertz PM, Eaglstein WH. Wound healing: The effect of topical antimicrobial agents. Arch Dermatol 1979; 115: 1311-1314.
28. Reich JD, Tarjan PP. Electrical stimulation of skin. Int J Dermatol 1990; 29: 395-401.
29. Castillo E, Sumano LH, Fortoul TI, Zepeda A. The influence of pulsed electrical stimulation on wound healing in burned rat skin. Arch Med Res 1995; 26: 185-189.
30. Casaubon TE, Sumano LH. Eficacia de la electroestimulacion en la cicatrizacion de las heridas y guemaduras en ratas por segunda intencion. Vet Mex 1991; 22: 284-289.
31. Sumano LH, Mateos TG. The use of acupuncture-like electrical stimulation for wound healing of lesions unresponsive to conventional treatment. Am J Acupunct 1999; 27: 5-15.
32. Sumano H, Goiz G, Clifford V. Use of electrical stimulation for wound healing in dogs. Israel J Vet Med 2002; 57: 31- 37.
33. Lee JA, Jeong HJ, Park HJ, Jeon S, Hong SU. Acupuncture accelerates wound healing in burn-injured mice. Burns 2011; 37: 117-125.
34. Zorlu U, Tercan M, Ozyazgan I, et al. Comparative study of the effect of ultrasound and electrostimulation on bone healing in rats. Am J Phys Med Rehabil 1998; 77: 427-432.
35. Omeroglu S, Cam M, Erdoğan D, et al. Streptozotosin ile deneysel diyabet oluşturulmuş sıçanlardaki deri yaralarında, insülin benzeri büyüme faktörü-I’in lokalizasyonunun immünohistokimyasal olarak gösterilmesi. Düzce Tıp Fakültesi Dergisi 2003; 5: 5-8.
36. Zhou J, Song Y, Wang Y. The study of epidermal growth factor skin wound healing. Chinese J Rep Rec Surg 1997; 11: 267-268.
37. Limaye PV, Sivakami S. Evaluation of the fluidity and functionality of the renal cortical brush border membrane in experimental diabetes in rats. Int J Biochem Cell Biol 2003; 35: 1163-1169.
38. Zhao H, Xu S, Wang Z, et al. Repetitive exposures to low- dose X-rays attenuate testicular apoptotic cell death in streptozotocin-induced diabetes rats. Toxicol Lett 2010; 192: 356-364.
39. Baynes J. Role of oxidative stress in development of complications in diabetes. Diabetes 1991; 40: 405-412.
40. Mallick C, Mandal S, Barik B, Bhattacharya A, Ghosh D. Protection of testicular dysfunctions by MTEC, a formulated herbal drug, in streptozotocin induced diabetic rat. Biol Pharm Bull 2007; 30: 84-90.
41. Ficher M, Zuckerman M, Fishkin RE, et al. Do endocrines play an etiological role in diabetic and nondiabetic sexual dysfunctions? J Androl 1984; 5: 8-16.
42. Agarwal A, Makker K, Sharma R. Clinical relevance of oxidative stress in male factor infertility, an update. Am J Reprod Immunol 2008; 59: 2-11.
43. Cai X, Jia H, Liu Z, et al. Polyhydroxylated fullerene derivative C(60)(OH)(24) prevents mitochondrial dysfunction and oxidative damage in an MPP(+) -induced cellular model of Parkinson's disease. J Neurosci Res 2008; 86: 3622-3634.
44. Zhang C, MA YX, Yan Y. Clinical effects of acupuncture for diabetic peripheral neuropathy. J Tradit Chin Med 2010; 30: 13-14.
45. Yin J, Chen J, Chen JD. Ameliorating effects and mechanisms of electroacupuncture on gastric dysrhythmia, delayed empting, and impaired accommodation in diabetic rats. Am J Physiol Gastrointest Liver Physiol 2010; 298: G563-570.
46. Tong Y, Jia Q, Sun Y, Hou Z, Wang Y. Acupuncture in the treatment of diabetic bladder dysfunction. J Altern Complement Med 2009; 15: 905-909.
47. Jing XH, Chen SL, Shi H, Cai H, Zin ZG. Electroacupuncture restores learning and memory impairment induced by both diabetes mellitus and cerebral ischemia in rats. Neurosci Lett 2008; 443: 193-198.
48. Kavakli A, Kose E, Akpolat N, Sarsılmaz M. The effects of acupuncture on rats with brain ischemia-reperfusion Neurosciences 2009; 14: 10-13.
49. Chu Q, Wang L, Liu GZ. Clinical observation on acupuncture for treatment of diabetic nephropathy. Zhongguo Zhen Jiu 2007; 27: 488-490.
50. Siterman S, Eltes F, Schechter L, et al. Success of acupuncture treatment in patients with initially low sperm output is associated with a decrease in scrotal skin temperature. Asian J Androl 2009; 11: 200-208.
51. Siterman S, Eltes F, Wolfson W, Lederman H, Bartoov B. Does acupuncture treatment affect sperm density in males with very low sperm count? A pilot study. Andrologia 2000; 32: 31-39.
52. Zhaohui Z, Yugui C, Yuanming Z, et al. Effect of acupuncture on pubertal development of rats and rabbits at different developmental stages. Neuropeptides 2007; 41: 249-261.
53. Zhao H, Tian Z, Feng Y, Chen B. Circulating estradiol and hypothalamic corticotrophin releasing hormone enhances along with time after ovariectomy in rats: effects of electroacupuncture. Neuropeptides 2005; 39: 433-438.
54. Liu CF, Yu LF, Lin CH, Lin SC. Effect of auricular pellet acupressure on oxidative systems in high-risk diabetes mellitus. J Altern Complement Med 2008; 14: 303-307.
55. Liu ZC, Liu JC, Zhang XZ, et al. Acupuncture prevents cognitive deficits and oxidative stress in cerebral multi- infarction rats. Neurosci Lett 2006; 393: 45-50.
56. Popova SP. Effect of acupuncture on dynamics of changes in lipid peroxidation and activity of antioxidant system in rats with gastroduodenal ulcer. Fiziol Zh 2002; 48: 54-59.