Bir Köpekte Dil Nekrozunda Trombositçe Zengin Plazma (PRP) Uygulaması

Bu olgu sunumu, nekrotik, ülseratif, yangılı glossit ile kliniğimize getirilen 6 yaşlı erkek Cocker Spaniel türü köpekte, trombositçe zengin plazma (PRP) uygulamasının klinik sonuçlarını ortaya koymaktadır. PRP, rejeneratif tıp dahilinde yerini almış, otolog ve uygulama kolaylığına sahip bir yöntem olup, literatürde bugüne kadar kanıtlanan rejenerasyon kabiliyetine rağmen, veteriner hekimlik alanında yeterince değerlendirilmediği kanaatindeyiz. Yöntemin daha fazla dikkate alınarak endikasyon dahilinde yaygınlaştırılması, ilgili alanlarda klinik başarıyı arttıracaktır.

Platelet Rich Plasma (PRP) Application in a Dog with Tongue Necrosis

This case report describes the clinical effects of platelet rich plasma (PRP) therapy in a 6 year old, male cocker spaniel with necrotic, ulcerative, inflammatory glossitis. PRP is a method, part of regenerative medicine, is an autologous and easily applied method with literature reports on its regenerative efficiency, but is not benefited properly in veterinary medicine. The authors state that consideration of this method within endication would bring clinical success in related areas.

___

  • 1. Marx RE, Carlson ER, Eichstaedt RM, et al. Platelet rich plasma: Growth factor enhancement for bone grafts. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1998; 85: 638-646.
  • 2. Villela DL, Santos VL. Evidence on the use of platelet-rich plasma for diabetic ulcer: A systematic review. Growth Factors 2010; 28: 111-116.
  • 3. Fallouh L, Nakagawa K, Sasho T, et al. Effects of autologous platelet-rich plasma on cell viability and collagen synthesis in injured human anterior cruciate ligament. J Bone Joint Surg Am 2010; 92: 2909-2916.
  • 4. Mooren RE, Hendriks EJ, van den Beucken JJ, et al. The effect of platelet-rich plasma in vitro on primary cells: Rat osteoblast-like cells and human endothelial cells. Tissue Eng Part A 2010; 16: 3159-3172.
  • 5. Chahal J, Geoffrey S, Van Thiel Mall N, et al. The role of platelet-rich plasma in arthroscopic rotator cuff repair: A systematic review with quantitative synthesis. The Journal of Arthroscopic & Related Surgery 2012; 28: 1718-1727.
  • 6. Shin MK, Lee JH, Lee SJ. Platelet-rich plasma combined with fractional laser therapy for skin rejuvenation. Dermatol Surg 2012; 38: 623-630.
  • 7. Li ZJ, Choi HI, Choi DK, et al. Autologous platelet-rich plasma: A potential therapeutic tool for promoting hair growth. Dermatol Surg 2012; 38: 1040-1046.
  • 8. Gawdat HI, Hegazy RA, Fawzy MM, et al. Autologous platelet rich plasma: Topical versus intradermal after fractional ablative carbon dioxide laser treatment of atrophic acne scars. Dermatologic Surgery 2014; 40: 152- 161.
  • 9. Nicoli F, Balzani A, Lazzeri D. Severe hidradenitis suppurativa treatment using platelet-rich plasma gel and Hyalomatrix. Int Wound J 2015; 12: 43-44.
  • 10. Lubkowska A, Dolegowska B, Banfi G. Growth factor content in PRP and their applicability in medicine. J Biol Regul Homeost Agents 2012; 26: 22-25.
  • 11. Textor J. Platelet-rich plasma (PRP) as a therapeutic agent: Platelet biology, growth factors and a review of the literature In: Lana JFSD, Santana A, Belangero D, Luzo M (Editors). Platelet-Rich Plasma Regenerative Medicine: Sports Medicine, Orthopedics and Recovery of Musculoskeletal Injuries", XVII, 2014, Springer Pub.
  • 12. Foster TE, Puskas BL, Mandelbaum BR. Platelet-rich plasma: From basic science to clinical applications. Am J Sports Med 2009; 37: 2259-2265.
  • 13. Sanchez-Gonzalez DJ, Mendez-Bolaina E, Trejo-Bahena NI. Platelet-rich plasma peptides: Key for regeneration. Int J Pept 2012; 3: 532-519.
  • 14. Carr BJ, Canapp SO, Mason DR, Cox C, Hess T. Canine platelet-rich plasma systems: A prospective analysis. Front Vet Sci "http://dx.doi.org/10.3389/fvets.2015.00073. 2015.
  • 15. Bosch G, van Schie HTM, Groot MW, et al. Effects of platelet-rich plasma on the quality of repair of mechanically induced core lesions in equine superficial digital flexor tendons: A placebo-controlled experimental study. Journal of Orthopaedic Research 2010; 28: 211-217.
  • 16. Franklin SP, Cook JL. Autologous conditioned plasma versus hyaluronan plus corticosteroid for treatment of chronic elbow osteoarthritis in dogs. Can Vet J 2013; 54: 881-884.
  • 17. Streckbein P, Kleis W, Buch RSR, et al. Bone Healing with or without Platelet-Rich Plasma around Four Different Dental Implant Surfaces in Beagle Dogs. Clinical Implant Dentistry and Related Research 2014; 16: 479-486.
  • 18. Jeong K, Kim SG, Lee JS, et al. Effect of platelet-rich plasma and platelet-rich fibrin on peri-implant bone defects in dogs. Journal of Biomedical Nanotechnology 2013; 9: 535-537.
  • 19. Karayannopoulou M, Psalla D, Kazakos G, et al. Effect of locally injected autologous platelet-rich plasma on second intention wound healing of acute full-thickness skin defects in dogs. Veterinary and Comparative Orthopaedics and Traumatology (VCOT) 2015; 3: 172-178.
  • 20. Monte JS, Monte LG, Oliveira NR, et al. Seropositivity to Leptospira interrogans canicola local isolate associated to tongue necrosis in dog without significant hematological alterations. Revista Brasileira de Higiene e Sanidade Animal 2013; 7: 157-166.
  • 21. Bruchim Y, Ranen E, Saragusty J, et al. Severe tongue necrosis associated with pine processionary moth (Thaumetopoea wilkinsoni) ingestion in three dogs. Toxicon 2005; 45: 443-447.
  • 22. Yıldar E, Güzel Ö. Tongue necrosis in a dog associated with the pine processionary caterpillar and its treatment. Turk J Vet Anim Sci Turk J Vet Anim Sci 2013; 37: 238- 241.
  • 23. Reiter AM. "Oral Inflammatory and Ulcerative Disease in Small Animals". https://www.merckvetmanual.com/ digestive-system/diseases-of-the-mouth-in-small-animals/ oral-inflammatory-and-ulcerative-disease-in-smallanimals/16.01.2017.
Fırat Üniversitesi Sağlık Bilimleri Veteriner Dergisi-Cover
  • ISSN: 1308-9323
  • Yayın Aralığı: Yılda 3 Sayı
  • Yayıncı: Prof.Dr. Mesut AKSAKAL
Sayıdaki Diğer Makaleler

Ornithobacterium rhinotracheale ile Enfekte Edilen Broylerlerde Lipid Peroksidasyon ve Bazı Antioksidanlar Üzerine Enrofloksasin ve Kafeik Asit Fenetil Ester'in Etkisi *

Osman GÜLER, Halil ŞİMŞEK, Ayşe KILIÇ, Mine ERİŞİR, Fulya BENZER, Bülent TAŞDEMİR, Sema TEMİZER OZAN

Bir Dağ Keçisinde (Capra aegagrus) Ateşli Silah Yaralanması Nedenli Beyin Travma Olgusu

Eren POLAT, Servet KILIÇ, Sema ÇAKIR

Biberiye Esansiyel Yağı ile Dekontaminasyonun Gökkuşağı Alabalıklarının (Oncorhynchus mykiss, W. 1972) Kalite Özellikleri Üzerine Etkisi *

Mehmet ÇALICIOĞLU, Emine ÖZPOLAT, Abdullah DİKİCİ, Bahri PATIR, Ahmet KOLUMAN

Simental Bir Buzağıda Görülen Fokomeli Olgusu

İbrahim CANPOLAT, Murat TANRISEVER

Aksaray Malaklı Köpeklerinde Columna Vertebralis'in Makro- Anatomik Olarak İncelenmesi

Zait Ender ÖZKAN, Ramazan İLGÜN, Sadık YILMAZ, Meryem KARAN

Geçiş Dönemindeki İneklerde Serum Bakır, Çinko, Manganez ve Kobalt Düzeyleri

Engin BALIKCI, Abdullah GAZİOĞLU

Afrika kedibalığı (Heterobranchus bidorsalis) için Antimikrobiyal Ajanlar olarak Tridax procumbens Yaprak Özü Potansiyelleri

Ibrahim ADESHINA, Mozeedah ABDULWAHAB, Yusuf Adetunji ADEWALE, Lateef Oloyede TIAMIYU

Türkiye'de Güvenli Hayvan Kurtarma

Pelin Fatoş POLAT, Halil Selçuk BİRİCİK, Gürbüz AKSOY

Kırsal Yoksullukla Mücadelede Hayvansal Üretim Desteği Uygulaması ve İllere Göre Dağılımı

Emin Ertan GÖKHAN

Malathionun Pullu Sazan (Cyprinus carpio)'da Paraoksonaz ve Arilesteraz Enzim Aktivitelerine Etkisinin Araştırılması

M. Enis YONAR, Tuğçe KILIÇ