Mustafa ARICAN, Mahmut OK, Tugce BAS, Gülsüm Boran ÇAYIRLI

Bir köpekte gastrik intestinal metaplazi

Olgunun materyalini, iştah kaybı, durgunluk, kilo kaybı, intermittankarakterde ishal ve 6 aydır tedaviye yanıt vermeyen kusma şikayetleri ile veteriner fakültesi hayvan hastanesine gelen 12 yaşlı erkekMaltese Terrier ırkı bir köpek oluşturdu. Klinik muayene, laboratuvar analizleri, ultrason muayenesi, endoskopik muayene, radyolojikmuayene, deneysel laparotomi ve histopatolojik inceleme sonucunda intestinal metaplazi tanısı konuldu. Köpeğe medikal tedavi olarak; kronik gastrit tedavisi uygulandı. Bu amaçla intravenöz 0.9%NaCl ve 5% dekstroz solüsyonları, vitamin ve aminoasit, maropitant,ranitidin, sukralfate, ve Seftriakson 2 hafta süreyle kullanıldı. 2 hafta süreyle uygulanan medikal tedaviye cevap alınmadığı görüldü veoperasyona sevk edildi. Pylorik antrumdan 1-1,5 cm ebatında biyopsi materyali alındı. Alınan biyopsi örneğinin histopatolojik incelenmesi sonucunda intestinal metapilazi tanısı konuldu. Operatif müdahale sonrası oral gıda alımı engellendi ve 10 gün parenteral beslemeyapıldı. Post-operatif dönem 30. gün aynı semptomların azalarakdevam ettiği gözlendi. Köpeklerin tedaviye cevap veremeyen kronikkusmalarında gastrik intestinal metaplazinin etkili olduğu saptandı.Hastalığın teşhisinde özellikle endoskopik muayene önemli katkısağlamakla birlikte lezyonunun tipini ve etiyolojisinde histopatolojikmuayene daha güvenilir olduğu kanısına varıldı

Gastric intestinal metaplasia in a dog

Aim: The material of the case was a 12-year-old male Maltese Ter rier dog who came to the veterinary faculty animal hospital with complaints of loss of appetite, stagnation, weight loss, intermit tent diarrhea and vomiting that did not respond to treatment for 6 months. Intestinal metaplasia was diagnosed as a result of clinical examination, laboratory analysis, ultrasound examination, endo scopic examination, radiological examination, experimental laparot omy and histopathological examination. As a medical treatment for the dog; chronic gastritis treatment was applied. For this purpose, intravenous 0.9% NaCl and 5% dextrose solutions, vitamins and amino acids, maropitant, ranitidine, sucralfate, and Ceftriaxone were used for 2 weeks. It was observed that there was no response to the medical treatment applied for 2 weeks and was referred to the oper ation. A 1-1.5 cm biopsy material was taken from the pyloric antrum. Intestinal metaplasia was diagnosed as a result of histopathological examination of the biopsy specimen taken. After the operative inter vention, oral food intake was prevented and parenteral feeding was given for 10 days. It was observed that the same symptoms contin ued to decrease on the 30th day of the post-operative period. Gastric intestinal metaplasia was found to be effective in chronic vomiting of dogs that did not respond to treatment. Although endoscopic exam ination made a significant contribution to the diagnosis of the dis ease, it was concluded that histopathological examination was more reliable in the type and etiology of the lesion

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