Baş ve boyun kanserli hastalarda gizli lenf nodu metastazı insidansı
Bafl ve boyun kanserli hastalarda gizli lenf nodumetastazı insidansı Amaç: Bu çalıflmanın amacı kliniğimize baflvuran bafl-boyun kanserli hastalarda saptanan gizli lenf nodu metastazı oranını belirlemektir. Yöntem:Kliniğimizde 2007 ile 2012 tarihleri arasında bafl ve boyunkanseri tanısı alan 107 hastanın dosyası retrospektif olarak incelendi.Tanı anında klinik ve radyolojik olarak N0 kabul edilen ve primer tümörün tedavisine ek olarak boyun diseksiyonu yapılan hastalar çalıflmaya dâhil edildi. Hastalar primer tümör tanısına göre gruplandırıldı. Hastaların patoloji sonuçları dokümante edildi ve lenf nodu metastazı olan hastalar tespit edildi. Gizli lenf nodu metastazına sahip hastaların oranı hesaplandı ve gizli lenf nodu metastazı ihtimali yüksekolan primer tümör bölgeleri belirlendi. Bulgular:Çalıflmamıza dahil edilen toplam hasta sayısı 64'tür. Altmıfldört hastanın 42'si (%65.6) larenks, 15'i (%23.4) oral kavite, 5'i (%7.8)parotis bezi, 1'i (%1.5) nazal kavite, geri kalan 1'i (%1.5) ise aurikulakanseri tanısı olan hasta idi. Larenks kanseri olan 12 (%70.5) hastada(4'ü supraglottik, 7'si transglottik ve 1'i glottik), oral kavite kanseri olan4 (%23.5) hastada ve parotis kanseri olan 1 (%5.8) hastada histopatolojik olarak lenf nodu metastazı mevcut idi. Larenks kanseri, supraglottik(n=4), transglottik (n=7) ve glottik (n=1) alt gruplarına ayrılmaktaydı. Enyüksek gizli lenf nodu metastaz oranı transglottik larenks kanserinde tespit edildi. Sonuç:Bafl boyun kanserlerinde gizli lenf nodu metastazı akılda tutulması gereken önemli bir konudur. Bu konuda önemli etkili hususise primer tümörün lokalizasyonudur. Bu çalıflma sonucunda transglottik larenks kanserlerinde gizli lenf nodu metastaz oranının yüksekolduğunu düşlünüyoruz.
Incidence of occult lymph node metastasis in patients with head and neck cancer
Objective:The objective of the study is to determine the incidence ofoccult lymph node metastasis detected in patients with head and neckcancer who applied to our clinic. Methods:Medical files of 107 patients who had been diagnosed ashead and neck cancer between 2007 and 2012 were retrospectivelyexamined. The patients who were accepted as N0 both clinically andradiologically at the time of diagnosis and those who had undergoneneck dissection in addition to the treatment of primary tumor wereincluded in the study. The patients were grouped based on the diagnosis of the primary tumor. Histopathology results of the patients andthose with lymph node metastasis were documented. The proportionof the patients with occult lymph node metastases was calculated andprimary tumor sites with a higher probability of occult lymph nodemetastases were determined. Results: A total of 64 patients were included in the study who were diagnosed as laryngeal (n=42; 65.6%), oral cavity (n=15; 23.4%), parotid gland(n=5; 7.8%), nasal cavity (n=1; 1.5%) and auricular (n=1; 1.5%) carcinomas.Histopathologically lymph node metastases were detected in patients withlaryngeal (n=12; 70.5%), oral cavity (n=4; 23.5%) and parotid gland (n=1;5.8%) carcinomas. Laryngeal cancers were subdivided into supraglottic(n=4), transglottic (n=7) and glottic (n=1) cancers. The highest rate ofmetastasis was detected in patients with transglottic laryngeal carcinoma. Conclusion:Occult lymph node metastasis is an important issue whichshould be kept in mind in cases with head and neck cancers. Location ofprimary tumor is an effective influential factor concerning this issue. Asa result of this study, we thought that occult lymph node metastases arefrequently seen in patients with transglottic laryngeal cancers.
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