FEVZİ SEFA DEREKÖY, Fethullah KENAR, GÜLİZ FATMA YAVAŞ, Tuncay KÜSBECİ, Faruk ÖZTÜRK, Abdullah AYÇİÇEK

İris rengi ve retina pigment epitel melanininin alerjik rinite olan etkisi

İris rengi ve retina pigment epitel melaninininalerjik rinite olan etkisi Amaç: Bu olgu kontrol çalışmasının amacı, iris rengi ve retina pigment epitel melanininin alerjik rinite olan etkisini saptamaktır. Yöntem:Çalışmaya 85 kontrol denek ve prospektif olarak alerjik rinit tanısı konan 99 hasta alındı. Göz muayenesinden sonra iris rengikaydedildi. Pupil dilatasyonundan sonra elektrookülografik ölçüm yapıldı ve Arden oranları kaydedildi. Bulgular:Yaş ortalaması alerjik rinitli hastalarda 29.44±9.8 yıl, kontrol deneklerde 32.67±12.9 yıl idi (p>0.05). Ölçülen Arden oranı ortalaması alerjik rinitli hastalarda 158.22±29.4, kontrol deneklerde179.34±29.3 idi (p

The influence of iris color and retina pigment epithelium melanin on allergic rhinitis

Objective:The purpose of this case control study is to establish theinfluence of iris color and retina pigment epithelium melanin on allergic rhinitis. Methods:Ninety-nine subjects diagnosed prospectively as allergicrhinitis and 85 control subjects were included in the study. Color of iriswas recorded after ophthalmic examination. Electro-oculographic measurement was done after pupil dilatation and Arden ratios were recorded.Results: Mean age was 29.44±9.8 years in subject with allergic rhinitisand 32.67±12.9 years in control subjects (p>0.05). Measured mean Ardenratio was 158.22±29.4 in subjects with allergic rhinitis and 179.34±29.3in normal subjects (p<0.05). In control group, Arden ratio was significantly higher in eyes with brown iris (p<0.05). In subjects with allergicrhinitis, Arden ratio was significantly lower in brown eyes (p<0.05).Conclusion:An association between allergic rhinitis and melanin content of iris and retina pigment epithelium was found. It can be speculated that pigment-producing system may play a role in the pathogenesis ofthe allergic rhinitis.

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