Kübra ARAL, CÜNEYT ASIM ARAL, Reyhan Ersin KALKAN

Astım ve Ağız Sağlığı

Astım, dünyada 300 milyondan fazla insanı etkileyen küresel bir sağlık sorunudur. Astım ve astım ilaçlarının diş çürüğü, dental erozyon ve periodontal hastalıklar ile olan ilişkisi literatürde sık olarak araştırılan bir konudur. Bu derlemenin amacı, astım ve astım tedavisinde kullanılan ilaçların, ağız sağlığı üzerine olan etkilerinin incelenmesi ve bu konuda alınabilecek önlemlerin değerlendirilmesidir.

Asthma and Oral Health

Asthma is a global health problem affecting more than three hundred million people around the world. The relationship between asthma, asthma medication and tooth decay, dental erosion, and periodontal disease has been extensively researched in the literature. The purpose of this review is to examinate the effects of asthma and asthma drugs on oral health, and to evaluate the precautions that may be taken in this regard.

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1. Bateman ED, Hurd SS, Barnes PJ, et al. Global strategy for asthma management and prevention: GINA executive summary. Eur Respir J 2008;31:143-178.
2. Lai CK, Beasley R, Crane J, et al. Global variation in the prevalence and severity of asthma symptoms: phase three of the International Study of Asthma and Allergies in Childhood (ISAAC). Thorax 2009;64:476-483.
3. Gomes-Filho IS, Soledade-Marques KR, Seixas da Cruz S, et al. Does periodontal infection have an effect on severe asthma in adults? J Periodontol 2014;85:e179-187.
4. Thomas MS, Parolia A, Kundabala M, Vikram M. Asthma and oral health: a review. Aust Dent J 2010;55:128-133.
5. McDerra EJ, Pollard MA, Curzon ME. The dental status of asthmatic British school children. Pediatr Dent 1998;20:281-287.
6. Ninan TK, Russell G. Respiratory symptoms and atopy in Aberdeen schoolchildren: evidence from two surveys 25 years apart. BMJ 1992;304:873- 875.
7. Sag C, Ozden FO, Acikgoz G, Anlar FY. The effects of combination treatment with a longacting beta2-agonist and a corticosteroid on salivary flow rate, secretory immunoglobulin A, and oral health in children and adolescents with moderate asthma: a 1-month, single-blind clinical study. Clin Ther 2007;29:2236-2242.
8. Shulman JD, Nunn ME, Taylor SE, RiveraHidalgo F. The prevalence of periodontal-related changes in adolescents with asthma: results of the Third Annual National Health and Nutrition Examination Survey. Pediatr Dent 2003;25:279- 284.
9. Stensson M, Wendt LK, Koch G, Oldaeus G, Ramberg P, Birkhed D. Oral health in young adults with long-term, controlled asthma. Acta Odontol Scand 2011;69:158-164.
10. Alaki SM, Ashiry EA, Bakry NS, Baghlaf KK, Bagher SM. The effects of asthma and asthma medication on dental caries and salivary characteristics in children. Oral Health Prev Dent 2013;11:113-120.
11. Ones U, Akcay A, Tamay Z, Guler N, Zencir M. Rising trend of asthma prevalence among Turkish schoolchildren (ISAAC phases I and III). Allergy 2006;61:1448-1453.
12. von Mutius E. The burden of childhood asthma. Arch Dis Child 2000;82 Suppl 2:II2-5.
13. Shashikiran ND, Reddy VV, Raju PK. Effect of antiasthmatic medication on dental disease: dental caries and periodontal disease. J Indian Soc Pedod Prev Dent 2007;25:65-68.
14. Kargul B, Tanboga I, Ergeneli S, Karakoc F, Dagli E. Inhaler medicament effects on saliva and plaque pH in asthmatic children. J Clin Pediatr Dent 1998;22:137-140.
15. O'Sullivan EA, Curzon MEJ. Drug treatments for asthma may cause erosive tooth damage. BMJ 1998;317:820.
16. Harding SM. Gastroesophageal reflux, asthma, and mechanisms of interaction. Am J Med 2001;111 Suppl 8A:8S-12S.
17. Barron RP, Carmichael RP, Marcon MA, Sandor GK. Dental erosion in gastroesophageal reflux disease. J Can Dent Assoc 2003;69:84-89.
18. Sivasithamparam K, Young WG, Jirattanasopa V, et al. Dental erosion in asthma: a case-control study from south east Queensland. Aust Dent J 2002;47:298-303.
19. Al-Dlaigan YH, Shaw L, Smith AJ. Is there a relationship between asthma and dental erosion? A case control study. Int J Paediatr Dent 2002;12:189-200.
20. Dugmore CR, Rock WP. Asthma and tooth erosion. Is there an association? Int J Paediatr Dent 2003;13:417-424.
21. Imfeld T. Prevention of progression of dental erosion by professional and individual prophylactic measures. Eur J Oral Sci 1996;104:215-220.
22. Ersin NK, Gulen F, Eronat N, et al. Oral and dental manifestations of young asthmatics related to medication, severity and duration of condition. Pediatr Int 2006;48:549-554.
23. Reddy DK, Hegde AM, Munshi AK. Dental caries status of children with bronchial asthma. J Clin Pediatr Dent 2003;27:293-295.
24. Ryberg M, Moller C, Ericson T. Saliva composition and caries development in asthmatic patients treated with beta 2-adrenoceptor agonists: a 4-year follow-up study. Scand J Dent Res 1991;99:212-218.
25. Bjerkeborn K, Dahllof G, Hedlin G, Lindell M, Modeer T. Effect of disease severity and pharmacotherapy of asthma on oral health in asthmatic children. Scand J Dent Res 1987;95:159- 164.
26. Eloot AK, Vanobbergen JN, De Baets F, Martens LC. Oral health and habits in children with asthma related to severity and duration of condition. Eur J Paediatr Dent 2004;5:210-215.
27. Ferrazzano GF, Sangianantoni G, Cantile T, Amato I, Ingenito A, Noschese P. Dental health in asthmatic children: a South Italy study. J Dent Child (Chic) 2012;79:170-175.
28. Lindemeyer RG, Satpute NS, Katz SH. Evaluation of bronchial asthma as risk factor for early childhood caries. J Mich Dent Assoc 2012;94:46- 49.
29. Natto ZS, Al-Zahrani MS. Periodontal bone loss and self-reported medical conditions in a dental school patient population. J Int Acad Periodontol 2010;12:104-109.
30. Card JW, Carey MA, Voltz JW, et al. Modulation of allergic airway inflammation by the oral pathogen Porphyromonas gingivalis. Infect Immun 2010;78:2488-2496.
31. Lenander-Lumikari M, Laurikainen K, Kuusisto P, Vilja P. Stimulated salivary flow rate and composition in asthmatic and non-asthmatic adults. Arch Oral Biol 1998;43:151-156.
32. Mandel ID, Eriv A, Kutscher A, et al. Calcium and phosphorus levels in submaxillary saliva. Changes in cystic fibrosis and in asthma. Clin Pediatr (Phila) 1969;8:161-164.
33. Wotman S, Mercadante J, Mandel ID, Goldman RS, Denning C. The occurrence of calculus in normal children, children with cystic fibrosis, and children with asthma. J Periodontol 1973;44:278- 280.
34. Irwin RS, Richardson ND. Side effects with inhaled corticosteroids: the physician's perception. Chest 2006;130:41S-53S.
35. Hanania NA, Chapman KR, Sturtridge WC, Szalai JP, Kesten S. Dose-related decrease in bone density among asthmatic patients treated with inhaled corticosteroids. J Allergy Clin Immunol 1995;96:571-579.
36. Mortimer KJ, Harrison TW, Tattersfield AE. Effects of inhaled corticosteroids on bone. Ann Allergy Asthma Immunol 2005;94:15-21; quiz 22- 13, 79.
37. Wactawski-Wende J. Periodontal diseases and osteoporosis: association and mechanisms. Ann Periodontol 2001;6:197-208.
38. Han ER, Choi IS, Kim HK, et al. Inhaled corticosteroid-related tooth problems in asthmatics. J Asthma 2009;46:160-164.
39. Hyyppa TM, Koivikko A, Paunio KU. Studies on periodontal conditions in asthmatic children. Acta Odontol Scand 1979;37:15-20.
40. Machado CC, Nojima Mda C, Rodrigues e Silva PM, Mandarim-de-Lacerda CA. Histomorphometric study of the periodontal ligament in the initial period of orthodontic movement in Wistar rats with induced allergic asthma. Am J Orthod Dentofacial Orthop 2012;142:333-338.
41. McNab S, Battistutta D, Taverne A, Symons AL. External apical root resorption of posterior teeth in asthmatics after orthodontic treatment. Am J Orthod Dentofacial Orthop 1999;116:545-551.