Melih BESTEL, Baki ERDEM, Ayşegül BESTEL, ONUR KARAASLAN

Agreement Between Endocervical Brush and Endocervical Curettage in the Diagnosis of Cervical

Cervical cancer is one of the most common gynecologic cancer, and endocervical curettage (ECC) and endocervical brush (ECB) can be used in the diagnosis of cervical cancer. In this study, it was aimed to investigate the agreement between two methods and evaluate whether more invasive ECC may be replaced with ECB. The data of obstetric patients who were admitted to the Gynecology and Obstetrics Clinic of a tertiary health care center in 2016 were retrospectively reviewed. A total of 170 patients were referred for colposcopy due to abnormal Papanicolaou test (Pap smear) results and / or high-risk human papilloma virus (HPV) positivity. All patients were examined without anesthesia through colposcopically directed biopsies and underwent cervical sampling with ECC and ECB. The ECB and ECC samples were grouped as negative, low-grade, and high-grade. ECB was negative in 132 (83.5%) of 158 patients with negative ECC results. Four patients with low-grade ECC results also had low-grade ECB results (100%). Of 8 patients with high-grade ECC results, only 4 patients (50%) had high-grade ECB results. Regarding all the data, a moderate degree of agreement was found between the two methods with an intraclass correlation coefficient of 0.503 (95% CI: [0.327-0.633], p

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