Nabi ZORLU, Didem DEMİR EKMEN, Serap POLAT, Ali KUSERLİ, Şeref GÜLSEREN

Normal Decision-making and executive functions in alcohol dependent individuals

Amaç: Karar verme (KV) süreci, bağımlılık alanındaki çalışmaların ana hedefi haline gelmiştir. Ancak, bağımlılarda sık görülen yüksek miktarda çoklu madde kullanımı ve psikiyatrik eştanı birlikteliği, KV çalışmalarının iki önemli yöntemsel kısıtlılığını oluşturmaktadır. Bu çalışmanın amacı, birinci ve ikinci eksende herhangi bir psikopatolojisi olmayan alkol bağımlılarında (AB) ve kontrol grubunda KV ve yürütücü işlevlerin karşılaştırılması ve KV ile yürütücü işlevler arasındaki ilişkinin araştırılmasıdır. Yöntem: Çalışmada 30 alkol bağımlısı erkek hasta ve 30 eşleştirilmiş sağlıklı erkek kontrol grubunun Iowa Kumar Testi (IKT), Wisconsin Kart Eşleme Testi, Stroop Testi, Sözel Akıcılık Testi ve İşitsel Üçlü Sessiz Harf Sıralaması Testi puanları karşılaştırılmıştır. Bulgular: Alkol bağımlısı grup ile sağlıklı kontrol grubu arasında, yapılan hiçbir testte herhangi bir anlamlı fark saptanmamıştır. Toplam grupta sadece işleyen bellek puanlarıyla KV arasında ilişki saptanmıştır. Sonuç: Sonuçlarımız, ‘saf’ AB’de IKT ile ölçülen KV’deki bozulmanın sadece alkol kullanımıyla sınırlı olduğunu ve genel bir bozulma olmadığını düşündürtmektedir.

Alkol bağımlılarında normal karar verme ve yürütücü işlevler

Normal decision-making and executive functions in alcohol dependent individuals Objective: Decision-making processes have become a principal target of study among addiction researchers. However, studies are often hampered by two significant methodological challenges: multi-substance dependence and comorbid conditions, which are independently associated with neurocognitive impairments. The purpose of this study was to compare alcohol dependent subjects without any comorbidity, with controls on a measure of decision-making and executive functions and to examine the interrelationship among these measures. Methods: We compared 30 alcohol-dependent (AD) male patients with 30 matched male healthy controls regarding their performances on the Iowa Gambling Task, Wisconsin Card Sorting Test, Stroop Test, Auditory Consonant Trigram Test and the Category Naming Test. Results: The AD group was not significantly more impaired compared to controls on any test. Only working memory scores were associated with decision-making scores in the total group. Conclusion: The results suggest that our sample of pure AD do not have global deficits in decision-making as measured by the IGT and that their poor decisions regarding their alcohol consumption are limited to drinking.

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