AĞIZ VE ÇENE CERRAHİSİNDE PERİOSTEUMUN GREFT OLARAK KULLANIMI: LİTERATÜR DERLEMESİ

Ağız ve çene cerrahisinde sert doku kayıplarının ona- rılmasında birçok materyal kullanılmaktadır. Kemik greftleri bu materyallerin başında gelmekte olup, oto- jen, allojen, ksenojen veya alloplastik olarak sınıflan- dırılırlar. Kemik greftlerinin osteokondüktif, osteojenik veya osteoindüktif özellikleri, bu materyallerin kulla- nılmasında ve iyileşme paterninde belirleyicidir. Periosteum; travma, tümör ve lenfosit mitojenlerin etkisiyle çoğalabilmek için uyarılabilme yetisine sahip osteoprogenitör hücreler ihtiva eden, bir kemik örtüsü olarak tanımlanabilir. Yapılan birçok çalışmada perios- teumun progenitör hücreleri sayesinde kıkırdak ve kemik rejenerasyonuna katkı sağladığı gösterilmiştir.Bu derleme çalışmasında, periosteal greftlerin osteojenik kapasitelerinin literatür ışığında açıklanması amaçlanmıştır. Anahtar kelimeler: Kemik grefti, periosteum kritik boyutlu defekti THE USAGE OF PERIOSTEUM AS A GRAFT MATERIAL IN ORAL AND MAXILLOFACIAL SURGERY: LITERATURE REVIEW ABSTRACTIn maxillofacial surgery, many graft materials have been used for the treatment of bony defects. Bone grafts are the main graft materials and they are classified as autogenous, allogeneic, xenogenic or alloplastic. The osteoconductive, osteogenic and osteoinductive properties of bone grafts determines the pattern of healing process and the utilization of the material. Periosteum can be defined as a bony cover that has osteoprogenitor cells with an ability of proliferation by trauma, tumor and lymphocyte mitogens. Most studies have shown periosteum promotes the bone and cartilage tissue regeneration.The aim of this review is the investigation of osteogenic capacity of periosteal grafts in literature. Keywords: Bone graft; periosteum; critcal size defect

Anahtar Kelimeler:

Kemik grefti

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