Kuntay KOKANALI, Esma SARIKAYA, Demet KOKANALI, Hatice KANSU ÇELİK, Özlem EVLİYAOĞLU, Burcu KISA KARAKAYA

Üreme çağındaki kadınlarda leiomiyosarkoma Hatice Kansu Çelik1, Burcu Kısa Karakaya1

Amaç: Uterin leiomyosarkomlar çok nadir tümörlerdendir. İleri yaş ve menapoz leiomyosarkomun potansiyel risk faktörleridir. Bu çalışmada, reprodüktif çağda leiomiyoma tanısı ile miyomektomi ya da histerektomi yapılan kadınlarda leiomiyosarkom insidansını saptamayı amaçladık Gereç ve Yöntem: 1 Ocak 2013 ile 1 Ocak 2015 tarihleri arasında leiomyioma tanısı ile miyomektomi ya da histerektomi yapılan reprodüktif çağdaki kadınlar retrospektif olarak tarandı. Leomiyosarkom insidansı hesaplandı. Hastaların yaşı, semptomları, operatif ve patolojik bulguları analiz edildi. Bulgular: Bu periyotta reprodüktif yaşta toplam 919 kadın opere edildi. 4 tane (%0,04) nadir primer uterus sarkomu saptandı. Vaka 1 ve vaka 3; 40 yaşında,vaka 2; 36 yaşında ve vaka 4; 39 yaşındaydı. Anormal uterin kanama ve pelvik ağrı malign vakaların en önemli iki semptomuydu. 3 hastaya myomektomi cerrahisi yapılırken, geri kalan 1 hastaya histerektomi operasyonu uygulandı. Sonuç: Leiomiyomanin tedavi seçenekleri hakkında danışmanlık verildiği sırada, leiomiyoma farzedilen oluşumun çok az da olsa malign çıkabileceği hakkında tüm kadınlar bilgilendirilmelidir.

Leiomyosarcoma during reproductive period

Purpose: Uterine leiomyosarcomas are exytremely rare tumors. Increased age and postmenopausal status are the potential risk factors of leiomyosarcomas. We aimed to determine the incidence of uterine leiomyosarcoma in women during reproductive period who undergoing hysterectomy or myomectomy for presumed benign leiomyomas.Materials and Methods: This retrospective study was carried out on women in reproductive age who had undergone myomectomy or hysterectomy due to presumed leiomyoma from January 1, 2013 to January 1, 2015. The incidence of leiomyosarcoma was calculated. Patient ages, admitting symptoms, and operative and pathologic findings were analyzed.Results: A total of 919 women in reproductive age underwent surgeries in the period of the study. We found four cases (0.40%) of rare primary sarcomas of uterus. Case-1 and Case-3 were a 40-year old women, Case-2 was a 36-year-old women, and Case-4 was a 39-year-old woman. Abnormal uterine bleeding and pelvic pain were the two symptoms in our malignant cases. 3 of the women underwent myomectomy procedure while one patient had hysterectomy.Conclusion: All women should be informed about quite minimal but potential possibility of malignancy that is present for their presumed leiomyomas during the counseling about the treatment options of leiomyomas.

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