Otizmli hastaların kardeşlerinin değerlendirilmesi ve kardeş sayı/sırasının hastalık şiddetine etkisi

Amaç: Bu çalışmada ilk amacımız otizmli hastaların ve tipik gelişim gösteren kardeşlerinin doğum öncesi, doğum ve premorbid özelliklerinin karşılaştırılması olup; ikinci amacımız kardeş sayı ve sırasının otizm şiddetine olan etkisini araştırmaktır. Gereç ve Yöntem: Çalışmaya 40 hasta (yaş ortalaması 89.83±42.91 ay) ile hastaların 18 kardeşi (yaş ortalaması 136.12±64.02 ay) dahil edilmiştir. 40 hastadan ortanca çocuk olan 6 hasta ve ikizi olan 1 hasta bu karşılaştırmaya dahil edilmemiştir. Kalan 33 hasta çalışmanın ikinci kısmı için; kardeşi olmayanlar (n:6); sadece yaşça büyük kardeş/leri olanlar (n:16) ve sadece yaşça küçük kardeş/leri olanlar (n:11) şeklinde üç gruba ayrılmıştır. Hastalık şiddetini belirlemek amacıyla Çocukluk Otizmi Derecelendirme Ölçeği (ÇODÖ) uygulanmıştır. Bulgular: Gebelik dönemi ile ilişkili değişkenlerde hastalar ve kardeşleri arasında anlamlı farklılık gözlenmedi. Hasta grupta yürüme, kelime söylemeye başlama, cümle kurma ve tuvalet eğitimi süreleri kardeşlerinden anlamlı olarak daha geç bulunmuştur. Görsel tepki, tatma, dokunma ve koklama tepkileri puanlamaları açısından anlamlı farklılık bulunmuştur.Sonuç: Kardeş ilişkisinin otizmde önemli olduğu bilinmektedir. Ancak otizm gibi etyolojisinde pek çok etmenin rol oynadığı bir hastalıkta belirti şiddetinin tek başına kardeş sayı ve sırasına bağlanamayacağı açıktır.

Anahtar Kelimeler:

otizm, sarılık, kardeş sayısı

Evaluation of siblings of patients with autism and the effect of sibling number/order on disease severity

Purpose: First aim of this study is comparing prenatal, natal and premorbid features of patients with autism and their typically development siblings; second aim is investigating the effect of sibling number and order on autism severity.Materials and Methods: 40 patients (mean age 89.83 ± 42.91 months) and 18 siblings (mean age 136.12 ± 64.02 months) were included in study. 6 patients who are the middle child and 1 patient with twin were not included of 40 patients. For the second part of study rest of 33 patients; who have no sibling/s (n: 6); only with older sibling/s (n = 16) and only with younger sibling/s (n: 11) were divided into three groups. The severity of autism symptoms of patients in these groups was compared. The Childhood Autism Rating Scale (CARS) was administered to determine the severity of the disease.Results: There were no significant differences between the patients and their siblings the variables associated with the prenatal period. The first walking, vocabulary, sentence formation and toilet training were significantly later in the patient group. Significant differences were found in terms of scores of visual response, tasting, touching and sniffing responses.Conclusion: Sibling relationship is important in autism. However it is clear that the symptom severity cannot be attributed only the number or order of siblings alonely which a lot of factors are involved in etiology of autism.

Keywords:

autism icterus, sibling number, sibling order,

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