Fatima AYAZ, Saeed Bin AYAZ, Sunila TASHFEEN, Muhammad FURRUKH

Gri trombosit sendromu

Gri trombosit (platelet) sendromu (GPS), trombositopeni ve ışık mikroskopunda soluk görünen kusurlu trombositlerle karakterize, otozomal resesif geçişli bir hastalıktır. Hastalarda kolay morarma, burun kanaması, menoraji ve uzun kanamalar görülmektedir. GPS için spesifik bir tedavi bulunmamaktadır dolayısı ile hastalığa karşı, riskleri öngörmek ve kanamanın önlenmesi için trombosit fonksiyonunu bozan ilaçlardan kaçınmak gerekmektedir. Bu olgu sunumunda, tekrarlayan anormal kanama atakları olan ve GPS bulgusu bulunan bir vaka sunulmaktadır.

Gray platelet syndrome

Gray platelet syndrome (GPS) is an autosomal recessive disorder characterized by thrombocytopenia and defective platelets that appear pale on light microscope. Patients present with easy bruisability, nose bleeds, menorrhagia and prolonged bleeding. There is no specific treatment for GPS and the management includes anticipating risks and preventing bleeding by avoiding drugs that impair platelet function. We present here report of a case who presented with repeated episodes of abnormal bleeding and was found to have GPS.

Keywords:

Bleeding disorder, gray platelet syndrome, thrombocytopenia,

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