Priapizmle başvuran bir orak hücreli anemili hastada korpus kavernozum trombozu
Priapizm orak hücreli aneminin bir komplikasyonu olarak görülebilen uzamış ağrılı ereksiyondur. Korpus kavernozum trombozu nadir görülen bir durumdur.Otuz yaşında bir orak hücreli anemi hastası priapizm şikayeti ile kliniğimize başvurdu. Hastaya korpus kavernozum aspirasyonu ve exchange transfüzyon uygulandı. Hastanın ağrılı ereksiyonu geriledi ancak ağrısı düzelmedi. Hastada korpus kavernozum trombozu saptandı ve sistemik antikoagülasyon tedavisi sonrası hastanın ağrısı düzeldi. Özellikle konvansiyonel tedavi yöntemleri ile şikayetleri devam eden hastalarda korpus kavernozum trombozu akılda tutulmalıdır.
Thrombosis of corpus cavernosum in a sickle cell anemia patient with priapism
Priapism is prolonged painful erection and can be seen as a sickle cell anemia complication.Thrombosis of the corpus cavernosum is a rare condition. A thirty years old male with of sickle cell anemia was admitted to our clinic with priapism. Corpus cavernosum aspiration and exchange transfusion were performed. Painful erection declined but the pain didn't improved. Corpus cavernosum thrombosis was detected and his pain relieved after systemic anticoagulation treatment. Thrombosis of corpus cavernozum must be in the mind especially for patients who have complaints despite conventional treatment methods.
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- 1. Gebreselassie S, Simmons MN, Montague DK. Genitourinary manifestations of sickle cell disease. Cleve Clin J Med. 2015;82:679-83.
- 2. Mulhall JP, Honig SC. Priapism: etiology and management. Acad Emerg Med. 1996;3:810-6.
- 3. Dean RC, Lue TF. Physiology of penile erection and pathophysiology of erectile dysfunction. Urol Clin North Am. 2005;32:379-95.
- 4. Hillis RS, Weems WL. Priapism: an unusual presentation. J Urol. 1976;116:124-5.
- 5. Johnson GR, Corriers JN Jr. Partial priapism. J Urol. 1980;124:147-8.
- 6. Ptak T, Larsen CR, Beckmann CF, Boyle DE Jr. Idiopathic segmental thrombosis of the corpus cavernosum as a cause of partial priapism. Abdom Imaging. 1994;19:564-6.
- 7. Llado J, Peterson LJ, Fair WR. Priapism of the proximal penis. J Urol. 1980;123:779-80.
- 8. Albrecht W, Stackl W. Treatment of partial priapism with an intracavernous injection of etilefrine. JAMA. 1997;277:378.
- 9. Gottesman JE. Recurrent partial priapism. Urology. 1976;7:519-20.
- 10. Goeman L, Joniau S, Oyen R, Oyen R, Claes H, Van Poppel H. Idiopathic partial thrombosis of the corpus cavernosum: conservative management is effective and possible. Eur Urol. 2003;44:119-23.
- 11. Horger DC, Wingo MS, Keane TE. Partial segmental thrombosis of corpus cavernosum: case report and review of world literature. Urology. 2005;66:194.
- 12. Machtens SA, Kuczyk MA, Becker AJ, Stief CG, Jonas U. Partial unilateral penile thrombosis: magnetic resonance imaging and management. J Urol. 1998;160:494-5.
- 13. Sparkenbaugh E, Pawlinski R. Interplay between coagulation and vascular inflammation in sickle cell disease. Br J Haematol. 2013;162:3-14.
- 14. Kato GJ, Taylor JG. Pleiotropic effects of intravascular haemolysis on vascular homeostasis. Br J Haematol. 2010;148:690-701.
- 15. Francis RB Jr, Johnson CS. Vascular occlusion in sickle cell disease: current concepts and unanswered
questions. Blood. 1991;77:1405-14.
- 16. Sparkenbaugh E, Pawlinski R. Priapism due to thrombosis in sickle cell anemia. Clin Proc Child Hosp Dist Columbia. 1947;3:241-3.
- 17. Yang YM, Donnell CA, Farrer JH, Mankad VN. Corporectomy for intractable sickle-associated priapism. Am J Med Sci. 1990;300:231-3.