Metilentetrahidrofolat redüktaz gen polimorfizmleri ve venöz tromboz

Anahtar Kelimeler:

Methylenetetrahydrofolate, reductase gene

Methylenetetrahydrofolate reductase gene polymorphisms and venous thrombosis

PDF

___

1. Kilicaslan B, Yazici N, Erol I, Erbay A. Retrospective evaluation of pediatric inpatients admitted with thrombosis according to risk factors: single center experience. Cukurova Med J. 2016;41:285-90.
2. Bauer KA, Lip GYH. Evaluating patients with established venous thromboembolism for acquired and inherited risk factors. https://www.uptodate.com/contents/evaluating-patients-with-established-venous-thromboembolism-for-acquired-and-inherited-risk-factors (accessed November 2016).
3. Bezemer ID, Doggen CJ, Vos HL, Rosendaal FR. No association between the common MTHFR 677C→T polymorphism and venous thrombosis: results from the MEGA study. Arch Intern Med. 2007;167:497-501.
4. Simone B, De Stefano V, Leoncini E, Zacho J, Martinelli I, Emmerich J et al. Risk of venous thromboembolism associated with single and combined effects of Factor V Leiden, Prothrombin 20210A and Methylenetethraydrofolate reductase C677T: a meta-analysis involving over 11,000 cases and 21,000 controls. Eur J Epidemiol. 2013;28:621-47.
5. Tsai AW, Cushman M, Tsai MY, Heckbert SR, Rosamond WD, Aleksic N et al. Serum homocysteine, thermolabile variant of methylene tetrahydrofolate reductase (MTHFR), and venous thromboembolism: Longitudinal Investigation of Thromboembolism Etiology (LITE). Am J Hematol. 2003;72:192-200.
6. Naess IA, Christiansen SC, Romundstad PR, Cannegieter SC, Blom HJ, Rosendaal FR et al. Prospective study of homocysteine and MTHFR 677TT genotype and risk for venous thrombosis in a general population-results from the HUNT 2 study. Br J Haematol. 2008;141:529-35.
7. van der Put NM, Gabreëls F, Stevens EM, Smeitink JA, Trijbels FJ, Eskes TK et al. A second common mutation in the methylenetetrahydrofolate reductase gene: an additional risk factor for neural-tube defects? Am J Hum Genet. 1998;62:1044-51.
8. Sazci A, Ergul E, Kaya G, Kara I. Genotype and allele frequencies of the polymorphic methylenetetrahydrofolate reductase gene in Turkey. Cell Biochem Funct. 2005;23:51-4.
9. von Depka M, Nowak-Göttl U, Eisert R, Dieterich C, Barthels M, Scharrer I et al. Increased lipoprotein (a) levels as an independent risk factor for venous thromboembolism. Blood. 2000;96:3364-8.
10. Sofi F, Marcucci R, Abbate R, Gensini GF, Prisco D. Lipoprotein (a) and venous thromboembolism in adults: a meta-analysis. Am J Med. 2007;120:728-33.