Kabakulak ve komplikasyonlarının değerlendirilmesi

Amaç: Kabakulağa bağlı komplikasyonların değerlendirilmesi, klinik ve dermografik özelliklerin araştırılması. Materyal ve Metod: Ocak 2001 - Ocak 2004 tarihleri arasında kabakulak nedeniyle başvuran 700 hasta değerlendirildi. Hastalar 5. gün kontrole çağırılarak komplikasyon gelişimi araştırıldı. 55 hasta parotit veya meningoensefalit gibi komplikasyonlar nedeniyle yatırılarak izlendi. Bulgular: Kabakulağa bağlı parotitisin her iki cinste eşit, en sık ilkbaharda görüldüğü ve ortalama yaşın 6.6 olduğu tespit edildi. Meningoensefalit geçiren hastalarda ise erkek: kız oranı 2:1, ortalama yaş 7.2, en sık ilkbaharda, sıklıkla ateş, kusma, baş ağrısı gibi şikayetlerle başvurdukları, uygunsuz ADH sendromu, trombositopeni, hidrosefali, ALT, AST yüksekliği, artralji gibi diğer komplikasyonların da eşlik ettiği belirlendi. Pankreatitte erkek : kız oranı 3:2, en sık ilkbaharda, ortalama yaş 7 olarak tespit edildi. Sonuç: Kabakulak nedeniyle başvuran ve komplikasyon gelişen hastalar akut dönemde tamamen iyileşirken kalıcı komplikasyon (hidrosefali) bir hastada izlendi. Bu hastamızda iyileşme 2 yıl sonra sağlandı.

Evaluation of mumps and complications

Objective: Evaluation of mumps' complications, determination of clinical and dermographical features of the patients. Materials and Methods: 700 patients applied to our hospital due to mumps between January 2001 and January 2004 were evaluated. Patients were asked to come on the 5th day after parotitis for observing the development of the complications. 55 patients were internated due to complications as parotitis or meningoensephalitis. Results: Mumps parotitis has been observed equally in both sexes, high frequently at spring and average age was 6.6 years. Mumps meningoencephalitis was observed more frequently in males and male : female ratio was 2:1, average age was 7.2 years, patients were admitted to hospital more often at spring with symptoms like fever, vomiting, headache. Other associated complications observed were syndrome of inappropriate ADH secrecion (SIADH) thrombocytopenia, mumps-associated hydrocephalus, elevation of liver enzymes as AST and ALT, arthralgia. In mumps pancreatitis male : female ratio was 3:2, average age was 7 years. Conclusion: All cases diagnosed with complications due to mumps had complete healing after acute stage, exept one patient having hydrocephalus who has complete remission after 2 years.

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  • 1.Gershon AA. Mumps. In: Katz SL, Gershon AA, Hotez PJ, eds. Krugman's Infectious Diseases of Children, 11th. ed. Mosby: Philadelphia, 2004:391-401.
  • 2.Comittee on Infectious Diseases, American Academy of Pediatrics, 2000 Red Book: Report of the Community on Infectious Diseases, Mumps: 405-8.
  • 3.Comittee on Infectious Diseases American Academy of Pediatrics, 2000 Red Book: Report of the Community on Infectious Diseases, Standart for Pediatric Immunization Practices: 748-58
  • 4.Kurt H. Kabakulak: In Willke-Topcu A, Söyletir G, Doğanay M, eds. İnfeksiyon Hastalıkları. İstanbul: Nobel Tip Kitabevi, 1996: 358-60.
  • 5.Kepa L, Oczko-Grzesik B, Stolarz W, Sobala-Szczygiel B. Extra-salivatory glands manifestations of mumps: Przegl Epide­miol 2002; 56: 391-8.
  • 6.Öktem F, Öztürk M, Olgar Ş. Kabakulak meningoensefaliti olan 51 hastanın değerlendirilmesi. Çocuk Dergisi 2003; 3: 213-6.
  • 7.Herzog C. Mumps epidemiology-worldwide. Soz Paraventivmed 1995: 40: 93-102.
  • 8.Kausas A. Clinical analysis of the patients with mumps. Medicina (Kaunas) 2002; 38: 1179-82.
  • 9.Bakasun. Mumps in the region of Rijeka, Croatia. Eur J Epidemiol 1997; 13: 117-9.
  • 10.Nardone A, Pebody RG, van den Hof S, et al. Sero-epidemiology of mumps in Western Europe. Epidemiol Infect 2003; 131: 691-701.
  • 11.Watson JC, Hadler SC, Dykewicz CA, et al. In CDC, Measles, Mumps and Rubella-vaccine use and strategies for elimination of measles, rubella, and congenital rubella syndrome and control of mumps. Recommendation of the Advisory Committee on Immunization Practice (ACİP). MMWR 1998; (RR-8): 1-57.
  • 12.Luca C, Luca V, Mihalache D, et al. Neurologic manifestation in mumps virus infection. Rev Med Chir Soc Med Nat Lasi 2000; 104: 83-6.
  • 13.Rodrigez-Vidigai F. Lymphocytic meningitis by mumps virus: epidemiologic, clinical, serological and evolutive analysis of 28 cases. Enferm İnfecc Microbiol Clin 1999; 17: 176-9.
  • 14.McDonald JC, Moore DL, Quennec P. Clinical and epidemiologic features of mumps meningoencephalitis and possible vaccine related disease; Pediatr Infect Dis J 1989; 8: 751-5.
  • 15.Donald PR, Burger PJ, Becker WB. Mumps meningo-encephalitis. S Afr Med J 1987; 71: 283-5.
  • 16.Uno M, Takano T, Yamano T, Shimoda M. Age dependent suseptibility in mumps-associated hydrocephalus: neuropathologic features and brain barriers. Acta Neuropathol (Berl) 1997; 94:207-15.
  • 17.Viola L, Chiaretti A, Castorina M, et al. Acute hydrocephalus as a consequence of mumps meningoencephalitis. Pediatr Emerg Care 1998; 14: 212-4.
  • 18.Chemtob S, Reece ER, Mills EL. Syndrome of inappropriate secretion of antidiuretic hormone in aseptic meningitis: Am J Dis Child 1985; 139: 292-4.
  • 19.Gündeş S, Wilke A, Özkan F, Vahapoğlu H. 2001 Yılı içersinde epididimoorşit komplikasyonuyla seyreden kabakulak vakalarının değerlendirilmesi, Klimik Dergisi, 2002; 15: 71-3.
  • 20.Rutkowska E, Pancewicz S, Szpakowicz T, et al. Hepatic re­ actions in the course of viral meningoencephalitis patients hospi­ talized in 1985-1989. Wiad Lek 1993; 46: 190-3.
  • 21. Skrha J, Stepan J, Sixtova E. Amylase isoenzymes in mumps. Eur J Pediatr 1979; 132: 99-105.
  • 22. Suskovic T, Vukicevic-Baudoin D, Vacicevi Z, Holjevac I. Severe pancreatitis as a first symptom of mumps complicated with pseudocyst and abscess of pancreas. Infection 1997; 25: 39-40.