Ziya SALİHOĞLU, Yıldız KÖSE, Şener DEMİROLUK, Saffet KARACA, Birsel EKİCİ

Sevofluranla tek soluk indüksiyonu ile propofol indüksiyonunun entübasyona hemodinamik yanıtlarının karşılaştırılması

Bu çalışmada propofol ile uygulanan intravenöz indüksiyonu ile, sevofluranla uygulanan tek soluk inhalasyon indük- siyon tekniğinin endotrakeal entübas- yon sonucu oluşan hemodinamik yanıt üzerine etkilerinin karşılaştırılması a- maçlandı.ASA I ve II gruplarına dahil 40 hasta rastlantısal olarak 20’şer kişilik Sevofluran ve Propofol gruplarına ayrıl- dı. Hastalara ameliyathanede premedi- kasyon olarak 1,5 mg/kg fentanil verildi. 2 dakika % 100 oksijen ile solutuldu. Sevofluran grubundaki hastalara %8 vol. sevofluran, %33 oksijen - %67 azot protoksit’den oluşan karışım, tek soluk inhalasyon indüksiyon tekniği ile uygu- landı. Kornea refleksi kaybolduktan sonra sevofluran konsantrasyonu %3’ü düşürüldü. Propofol grubundaki hasta- lara ise 2 mg/kg intravenöz propofol ve- rildi. Kornea refleksi kaybolduktan son- ra %33 oksijen-%67 azot protoksit ile ventile edildi. Bütün hastalara 0,1 mg/kg vekuroniyum intravenöz sonrası endotrakeal entübasyon uygulandı. Hastaların ortalama arter basınçları, kalp atım hızları ve oksijen satüras- yonları kaydedildi. Sevofluranla uygula- nan tek soluk inhalasyon indüksiyon tekniği ile propofolle uygulanan intra- venöz indüksiyon tekniğinin endo- trakeal entübasyon sonucu oluşan he- modinamik yanıt üzerine etkileri ara- sında istatistiksel olarak anlamlı fark bulunmadı. Fakat ortalama arter ba- sınçları entübasyon sonrası 1.dakikada propofol grubunda başlangıç değerleriy- le karşılaştırıldığında istatistiksel ola- rak anlamlı bir artış gösterdi (p

Effects of propofol versus single inhalation with sevorane on hemodynamic responses to endotracheal entubation

In this study we aimed to compare single breath with sevoflurane and propofol intravenous induction for responses to tracheal intubation. ASA I-II groups 40 patients were included in this study. They were randomly allocated into two groups as sevoflurane (n=20) and propofol groups (n=20). As premedication, 1,5 mg/kg fentanyl was administered intravenously. Patients were breathed 100 % oxygen during 2 minutes period. In the sevoflurane group, 8 % vol sevorane, 33 % oxygen 67 % N2O mixture was breathed with single breath technique. When cornea reflex disappeared, sevorane concentration decreased 3 % of the volume. In propofol group, 2 mg/ kg propofol was administered intravenously. Patients were breathed 33 % oxygen 67 % N2O mixture. After 0,1 mg/kg vecuronium administration, endotracheal entubation was performed. Mean arterial pressure, heart rate and oxygen saturation values was enrolled. Results.- There were no difference with all measuring parameters. Only in the propofol group there was significantly decrease in MAP at the first minute (p

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