Sıçanlarda mandibular kondilin histolojik yapısı üzerine cinsiyetin etkilerinin histomorfometrik olarak incelenmesi

Bu çalışma sıçanlarda mandibular kondilin histolojik yapısı üzerine cinsiyetin etkilerinin belirlenmesi amacıyla gerçekleştirildi. Çalışmada erişkin, sağlıklı 5 dişi ve 5 erkek olmak üzere toplam 10 adet Wistar Albino sıçan kullanıldı. Dişi ve erkek sıçanlar Ketamin HCI anestezisi altında sakrifiye edilerek, histolojik ve histomorfolojik prosedürle incelendi. Mandibular kondil kıkırdağının toplam kalınlığı erkeklerde 86,05 μm, buna karşın dişilerde ise 138,58 μm olarak ölçüldü. Kıkırdak katmanlarından proliferatif, kondrojenik ve hipertrofik bölgelerin kalınlığı erkek ve dişi sıçanlar arasında istatistiki anlamda önemli bulundu (P

Histomorphological evaluation of the effects of gender on the histological structure of mandibular condyle in rats

This study was performed to determine the effects of gender on the histological structure of rat mandibular cartilage. A total of 10 mature Wistar albino rats were divided into male and female groups comprising 5 animals each. Following the sacrification of male and female rats by Ketamin HCl anaesthesia, they were investigated by using histological and histomorphological procedures. Total thicknesses of the mandibular condyle cartilage of males and females were 86.05 and 138.58 μm, respectively. Among the cartilage layers, the thickness of proliferative, chondrogenic and hypertrophic zones were significantly different between the genders. As a result, the thickness of mandibular condyle cartilage of female rats was significantly higher than that of males.

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