MR ile incelenen lomber disklerdeki difüzyon değerlerinin dejenerasyonla ve yaşla olan ilişkisi

Amaç: Bu çalışmada lomber disklerdeki difüzyon değerlerinin dejenerasyonla ve yaşla olan ilişkisi ADC ölçümleriyle değerlendirildi. Gereç ve Yöntem: Bel ağrısı yakınmasıyla başvuran yaşları 14-64 arasında değişen 50 olguya (24 kadın, 26 erkek) difüzyon ağırlıklı MR görüntüleme uygulandı. T2 ağırlıklı sagital görüntülerde dejenere diskler belirlendi. Dejenere diskler hafif ve ağır olarak gruplandırıldı. Her bir disk düzeyi için ADC değerleri ölçüldü. Normal disklerin ortalama ADC değerlerinin anatomik düzeyle ve yaşla olan ilişkisi değerlendirildi. Dejenere disklerin ortalama ADC değerleri normal disklerle karşılaştırıldı. Bulgular Mann Whitney testi, Kruskal Wallis testi ve Sperman’s korelasyon katsayısıyla analiz edildi. Bulgular: Ortalama ADC değerleri normal disklerde 1.82 ± 0.20 x 10-3 mm2/sn, dejenere disklerde 1.30 ± 0.47 x 10-3 mm2/sn olarak bulundu (p< 0.01). Normal disklerde anatomik düzeyle ortalama ADC değerleri arasında anlamlı ilişki saptanmadı. Yaşla ortalama ADC değerleri arasında negatif korelasyon yönünden anlamlı ilişki mevcuttu. Sonuç: Dejenere disklerin ADC değerleri normal disklere göre belirgin olarak azalmıştır. Dejeneratif disk hastalığının değerlendirilmesinde difüzyon MR görüntüleme son derece faydalı bir yöntem olabilir

The correlation of the diff usion values in lumbar intervertebral discs with disc degeneration and age

PURPOSE: To evaluate the correlation of the diffusion values in lumbar intervertebral discs with disc degeneration and age. MATERIALS AND METHODS: Diffusion-weighted imaging of the lumbar spine was performed in fifty patients. ADC values were recorded for each disc. All discs were visually as being normal or as showing at least one of two MR findings of degeneration on sagittal T2 weighted images. Mean ADC values of normal discs were compared with those of degenerated discs and were correlated with age and anatomic location. Data were analyzed by using Mann Whitney test, Kruskal Wallis test, and Sperman s correlation statistics. RESULTS: The mean ADC value was 1.82 ± 0.20 x 10-3 mm2/sec in normal discs and 1.30 ± 0.47 x 10-3 mm2/sec in abnormal discs. No a statistically signicifant dependence of lumbar disc ADC on anatomic location was reported. There was a correlation between age and mean ADC values of lumbar discs. CONCLUSION: A statistically significant decrease was seen in the ADC values of degenerated lumbar discs when compared with ADC values of normal discs. Diffusion MR imaging may be useful technique in the evaluation of degenerative disc disease.

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