FARMASÖTİK BİR PREPARATTAKİ İKİLİ KARIŞIMIN SPEKTROFOTOMETRİK SİNYAL İŞLEME TEKNİĞİ KULLANILARAK AYNI ANDA MİKTAR TAYİNİ VE VALİDASYONU

Amaç: Bu çalışmada, tablette irbesartan (IRB) ve hidroklorotiyazidin (HCT) aynı anda miktar tayini için hızlı ve güçlü bir sinyal işleme yaklaşımı, spektrum oranları türev spektrofotometri (RDS) yöntemi geliştirilmiştir. RDS yöntemi, IRB ve HCT'nin UV spektrumlarına uygulanmıştır.

SIMULTANEOUS QUANTITATIVE RESOLUTION AND VALIDATION OF A BINARY MIXTURE IN A PHARMACEUTICAL DOSAGE FORM BY USING A SPECTROPHOTOMETRIC SIGNAL PROCESSING TECHNIQUE

Objective: In this context, a rapid and powerful signal processing approach, a ratio-derivative spectrophotometry (RDS) method were developed for the simultaneous determination of irbesartan (IRB) and hydrochlorothiazide (HCT) in a tablet.

Keywords:

Derivative, quantitative determination, spectrophotomety signal processing, validation,

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