Zehra KURDOĞLU, Burak KARADAĞ, Yusuf ERGÜN, Yetkin KARASU, Vakkas KORKMAZ, Duygu CÖMERT KAVAK, Ezgi TURGUT, Nuri ŞENGÜLEROĞLU, Canan DEVECİ DURA

GEBELİK BOYUNCA D VİTAMİNİ TAKVİYESİ PRETERM DOĞUM ORANINI AZALTIR MI?

AMAÇ: Gebe kadınlarda D vitamini eksikliği yaygındır. Birçok çalışmada D vitamini eksikliği ile anormal gebelik sonuçları arasında pozitif ilişki gösterilmiştir. Bu çalışmadaki amacımız D vitamini takviyesi yapılan ve yapılmayan gebelerde gebelik sonuçlarının karşılaştırılmasıdır.GEREÇ VE YÖNTEM: Çalışmaya 150 gebe dahil edildi ve gravide, parite, abortus, gebelik haftası, ek hastalık, sigara kullanımı, diyet, gebelik komplikasyonları, 1. ve 5. dakika Apgar skoru, doğum kilosu, umblikal kord pH'sı ve D vitamini takviyesi açısından değerlendirildi.BULGULAR: Dahil edilen gebelerin 70'i D vitamini takviyesi almış iken, kalan 80 'i almamıştı. Gravide, parite, abortus, ek hastalık, sigara kullanımı, diyet, gebelik komplikasyonları, 1. ve 5. dakika Apgar skoru, doğum kliosu, umblikal kord pH'sı iki grup arasında benzerdi (P> 0,05). Kontrol grubunda, çalışma grubuna göre doğum haftası daha erken idi (P= 0,002). Gebelik komplikasyonları çalışma grubunda kontrol grubuna göre daha az idi (P= 0,042). SONUÇ: Gebelik sırasında D vitamini takviyesi özellikle preterm doğum olmak üzere daha düşük gebelik komplikasyonları ile ilişkilidir. Gebelikte D vitamini takviyesinin rolünü değerlendiren randomize çalışmalar gereklidir.

DOES VITAMIN D SUPPLEMENTATION DURING PREGNANCY REDUCE PRETERM BIRTH RATE?

OBJECTIVE: Vitamin D deficiency is common among pregnant women. Several studies have demonstrated a positive association between vitamin D status and adverse pregnancy outcomes. The aim of our study is to compare the pregnancy outcome in women received vitamin D supplementation or not.MATERIAL AND METHODS: One hundred and fifty consecutive pregnant women were enrolled in this study and evaluated in terms of gravidity, parity, abortion, gestational age, comorbidity, smoking, diet, pregnancy complications, Apgar score at 1 and 5 minute, birth weight, umbilical cord pH and receiving vitamin D supplementation.RESULTS: Out of 70 women received vitamin D supplementation during pregnancy, 80 of these women were not. Gravidity, parity, abortion, gestational age, comorbidity, smoking, diet, pregnancy complications, Apgar score at 1 and 5 minute, birth weight and umbilical cord pH were similar between groups (P> 0.05). In control group, gestational week at delivery was earlier than study group (P= 0.002). Pregnancy complications in study group were fewer than control group (P= 0.042).CONCLUSION: Vitamin D supplementation during pregnancy is associated with fewer pregnancy complications, especially preterm delivery. Further randomised trials are required to evaluate the role of vitamin D supplementation in pregnancy.

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