Gürkan ATAY, Bülent ALİOĞLU, Rukiye SAÇ ÜNSAL, Yıldız Bilge DALLAR, Meryem ÖNDER, Esra TAPCI, Volkan CAN

DEMİR EKSİKLİĞİ ANEMİSİ OLAN ÇOCUKLARDA FERRO-GLİSİN-SÜLFAT, FERRİK-HİDROKSİT KOMPLEKSİ İLE FERRO-GLİSİN-SÜLFAT VE ORAL ÇİNKO KOMBİNASYONUNUN KARŞILAŞTIRILMASI: RETROSPEKTİF ÇALIŞMA

AMAÇ: Bu çalışmada okul öncesi çocuk çağı demir eksikliği anemisi (DEA) hastalarında farklı demir preparatlarının tedavi üzerine etkisi amaçlandı. GEREÇ VE YÖNTEMLER: Çalışmaya retrospektif olarak 150 hasta alındı. Tüm bilgiler hastaların dosyalarından alındı. Çocuklar üç gruba ayrıldı: Demir II-glisin-sülfat kompleksi (demir II), demir III-hidroksit-polimaltoz kompleksi (demir III) ve demir II-çinko kombinasyonu. BULGULAR: Demir II tedavisi alan hastalar hematolojik testleri ve ferritin değerleri göz önüne alındığında demir III ve demir II-çinko kombinasyonuna göre daha etkin olduğu saptandı. SONUÇ: Demir II içeren preparatlar DEA tedavisinde diğer preparatlara göre daha etkindir. Demir eksikliği anemisi olan çocuklarda demir II preparatlarının tek başına kullanılması gerektiğini vurgulamak isteriz.

EFFICACY OF FERROUS-GLYCINE-SULPHATE VERSUS FERRIC-HYDROXIDE- POLYMALTOSE COMPLEX, AND FERROUS-GLYCINE-SULPHATE AND ORAL ZINC SULPHATE COMBINATION IN CHILDREN WITH IRON DEFICIENCY ANEMIA: RETROSPECTIVE STUDY

OBJECTIVE: This study aimed to assess treatment effects and the results of various oral iron preparations for iron deficiency anemia (IDA) treatment in preschool children. MATERIAL AND METHODS: Retrospectively, totally 150 children were included in this study. All data of the patients with IDA were obtained from their hospital folders. Children were randomized into three groups as follows: children who were treated with iron II-glycine-sulphate complex (iron II), iron III-hydroxide-polymaltose complex (iron III), and a preparation with iron II-zinc combination, respectively. RESULTS: Treatment with iron II was determined to be more effective than treatment with iron III or the iron II-zinc combination with regards to hematological tests and ferritin values after the treatment. CONCLUSION: In conclusion, it was determined that preparations containing only iron II are more effective in the treatment of IDA. We emphasize that iron II preparations should be used alone for IDA treatment considering the results obtained from the groups treated with iron III and iron II-zinc combination.

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