Kontrollü hipotansiyon endoskopik sinüs cerrahisinde kanamayı azaltarak cerrahi sahanın görüşünü artırmak ve operasyonun süresini kısaltmak için uygulanan bir yöntemdir. Kan başmandaki değişikliklerin, özellikle hipotansiyonun kognitif fonksiyonları etkilediği çeşitli çalışmalarda gösterilmiştir. Bu çalışmada, endoskopik sinüs cerrahisi gibi kan basıncının düşük olması gereken operasyonlarda uygulanan kontrollü hipotansiyonun, postoperatif dönemde kognitif fonksiyonlara ve derlenmeye etkisini araştırmayı amaçladık. Üniversite etik kurul onayı ve hasta yazılı onamları alındıktan sonra, endoskopik sinüs cerrahisi uygulanacak 46 hasta çalışmaya dahil edildi ve randomize olarak iki gruba ayrıldı; Normotansif anestezi grubu (Grup N, n=23) ve Hipotansif anestezi grubu (Grup H, n=23). Anemisi olan (Hb

Controlled hypotansive anaesthesia has been used during surgical procedures in an attempt to reduce intraoperative hemorrhagefor reducing operation time. Previous reports show that differences in blood pressure, especially hypotension affects cognition. We aimed to investigate the effect of hypotensive anaesthesia on cognitive functions in endoscopic sinüs surgery, which requires decreased blood pressure. After obtaining approval from The University Hospital Ethics Committee, 46 adults of both sexes, undergoing elective endoscopic sinüs surgery were allocated to Group N: The normotensive anaesthesia group, and 23 patients were allocated to Group H: The hypotensive anaesthesia group. Exclusion criteria were: patient age<17 and >55, patients mth anaemia (Hb<10gr $dl^-1$ ), hypovolemia, cardiovascular disease, renal and hepatic insufficiency, cerebrovascular disease and glaucoma far both groups. Propofol infusion was used to maintain anaesthesia mth oxygen and nitrous oxide. Hypotensive anaesthesia was induced with NTG infusion at 1% concentration in 5% dextrose solution to maintain the mean arterial pressure between 50-60 mm Hg. We used the Mini Mental State Examination Tests (MMSET) and Visual Aural Digit Span Test (VADST)for neurocognitive performance obtained prior to surgery and repeated at 2rd and 24th hours after the operation. Postoperative recovery was assessed using the Aldrete Post Anaesthesia Recovery Score. The preoperative differences between the normotensive and hypotensive groups were not statistically significant. Blood pressures and blood loss were significantly lower in Group H in all the measurements (p<0.05). Recovery scores at 15th minute were significantly lower in Group N than Group H but there were no differences from 30th minute scores. There were no significant differences bettveen the two groups in cognitive test scores at ali the measurement times. it was concluded that hypotensive anesthesia is valuable in reducing blood loss and did not cause cognitive dysfunction in the early post operative period.