Yaygın gelişimsel bozukluğu olan çocukların kardeşlerinde psikopatoloji

Amaç: Bu makalede yaygın gelişimsel bozukluk (YGB) tanısı konan çocukların kardeşlerinde görülen gelişimsel problemlerle psikososyal uyum problemlerinin gözden geçirilmesi amaçlanmıştır. Yöntem: Bu amaçla medline taraması yapılmış, konu ile ilişkili kitaplar ve bu kardeşlerde yapılan araştırmalar incelenmiştir. Bulgular: Bulgular bu kardeşlerde YGB spektrum bozukluklarının yanı sıra, herhangi bir YGB tanısını karşılamayan eşik altı prob-lemlerin görülme sıklığının arttığına dikkat çekmektedir. Bu kardeşlerin gerek motor gelişiminde, gerekse dil gelişiminde gecikme ve sapmalar olduğu bildirilmektedir. Her ne kadar bazı araştırmalarda uyumlarının, kontrol-lerden farklı olmadığı gösterilmişse de, diğerlerinde artmış uyum problemleri, yüksek depresyon oranları ve özel-likle içselleştirici problemler için artmış riske sahip olduklarına dikkat çekilmektedir. Tartışma: Taşıdıkları kalıtsal ve psikososyal yükler nedeniyle YGB tanılı çocukların kardeşleri psikopatoloji için risk altındadır. Bu bağlamda bu kardeşlerin psikiyatrik açıdan değerlendirilmeleri erken tanı ve müdahalelere olanak sağlayacaktır. Ancak bu alan-da yapılmış çalışmaların oldukça az sayıda olması bu kardeşlerde yapılacak uzunlamasına izleme çalışmalarına olan gereksinmenin altını çizmektedir.

Psychopathology in siblings of children with pervasive developmental disorders

Objective: In this article developmental and psychosocial adjustment problems observed in siblings of children with pervasive developmental disorders (PDD) are reviewed. For this purpose, medline was searched and books related with the subject and previous studies related with these siblings were examined. Results: Findings draw attention to the increase in the prevalence of PDD spectrum disorders and subthreshold problems which do not meet the diagnostic criteria for PDD in siblings of children with PDD. It has been reported that these siblings have delay and deviance in motor and language development. Although some studies have demonstrated that their adjustment are not different than controls, others draw attention to the increased risk they have for adjustment problems, high depression rates and especially for internalizing problems. Discussion: Because of the hereditary and psychosocial loadings they have, siblings of children with PDD are at risk for psychopathology. Psychiatric evaluation of the siblings in this context will make early diagnosis and intervention possible. The limited number of studies in this area, highlights the need for longutidunal follow-up studies which will be done with these siblings.

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1.Volkmar FR, Lord C, Klin A, Schultz R, Cook EH. Autism and the pervasive developmental disorders. A Martin, FR Volkmar (Eds.), Lewis's Child and Adolescent Psychiatry, fourth ed., Philadelphia, Lippincott Williams and Wilkins, 2007, p. 384-400.

2.Chakrabarti S, Fombonne E. Pervasive developmental disorders in preschool children: confirmation of high prevalence. Am J Psychiatry 2005; 162:1133-1141.

3.Veenstra-Vanderweele J, Cook EHJ. Genetics of childhood disorders: XLVI. autism, part 5: Genetics of autism. J Am Acad Child Adolesc Psychiatry 2003; 42:116-118.

4.Bailey AJ. The biology of autism. Psychol Med 1993;23:7-11.

5.Glasberg BA. The development of siblings' understanding of autism spectrum disorders. J Autism Dev Disord 2000; 30:143-156.

6.Rodrigue JR, Geffken GR, Morgan SB. Perceived competence and behavioral adjustment of siblings of children with autism. J Autism Dev Disord 1993; 23:665-674.

7.Gray DE. Autism and the Family: Problems, Prospects and Coping with the Disorder. Illinois, Springfield, 1998, p.23-97.

8.Macks RJ, Reeve RE. The adjustment of non-disabled siblings of children with autism. J Autism Dev Disord 2007; 37:1060-1067.

9.Iverson JM, Wozniak RH. Variation in vocal-motor development in infant siblings of children with autism. J Autism Dev Disord 2007; 37:158-170.

10.Karabekiroğlu K, Akbaş S. Kafa çevresi farkı otizmde neden ve ne zaman başlıyor? Anadolu Psikiyatri Derg 2008; 9:31-38.

11.Pilowsky T, Yirmiya N, Shalev RS, Gross-Tsur V. Language abilities of siblings of children with autism. J Child Psychol Psychiatry 2003; 44:914-925.

12.Gamliel I, Yirmiya N, Sigman M. The development of young siblings of children with autism from 4 to 54 months. J Autism Dev Disord 2007; 37:171-183.

13.Yirmiya N, Shaked M. Psychiatric disorders in parents of children with autism: a meta-analysis. J Child Psychol Psychiatry 2005; 46:69-83.

14.Yirmiya N, Gamliel I, Pilowsky T, Feldman R, Baron-Cohen S, Sigman M. The development of siblings of children with autism at 4 and 14 months: Social engagement, communication, and cognition. J Child Psychol Psychiatry 2006; 47:511-523.

15.Toth K, Dawson G, Meltzoff AN, Greenson J, Fein D. Eady social, imitation, play, and language abilities of young non-autistic siblings of children with autism. J Autism Dev Disord 2007; 37:145-157.

16.August GJ, Stewart MA, Tsai L. The incidence of cognitive disabilities in the siblings of autistic children. Br J Psychiatry 1981; 13:416-422.

17.Gillberg C, Gillberg IC, Steffenburg S. Siblings and parents of children with autism: A controlled population- based study. Dev Med Child Neurol 1992; 34:389-398.

18.Boutin P, Maziade M, Merette C, Mondor M, Be'tard C, Thivierge M. Family history of cognitive disabilities in first-degree relatives of autistic and mentally retarded children. J Autism Dev Disord 1997; 27:165-176.

19.Szatman P, Jones MB, Tuff L, Bartolucci G, Fis-man S, Mahoney W. Lack of cognitive impairment in firstdegree relatives of children with pervasive developmental disorder. J Am Acad Child Adolesc Psychiatry 1993; 32:1264-1273.

20.Narayan S, Moyes B, Wolff S. Family characteristics of autistic children: A further report. J Autism Dev Disord 1990; 20:523-535.

21.Pilowsky T, Yirmiya N, Gross-Tsur V, Shalev RS. Neuropsychological functioning of siblings of children with autism, siblings of children with developmental language delay, and siblings of children with mental retardation of unknown genetic etiology. J Autism Dev Disord 2007; 37:537-552.

22.Baron-Cohen S, Hammer J. Parents of children with Asperger syndrome: What is the cognitive phenotype? J Cogn Neurosci 1997; 9:548-554.

23.Constantino J, Lajonchere C, Lutz M, Gray T, Abbacchi A, McKenna K, et al. Autistic social impairment in the siblings of children with pervasive developmental disorders. Am J Psychiatry 2006; 163:294-296.

24.Bailey A, Palferman S, Heavey L, Le Couteur A. Autism: The phenotype in relatives. J Autism Dev Disord 1998; 28:369-392.

25.Micali N, Chakrabarti S, Fombonne E. The Broad Autism phenotype: findings from an epidemiological survey. Autism 2004; 8:21-37.

26.Bryson SE. Epidemiology of autism: Overview and issues outstanding. DJ Cohen, FR Volkmar (Eds.), Handbook of Autism and Pervasive Developmental Disorders, second ed., New Jersey, John Wiley and Sons, 1997, p.41-46.

27.Cassel TD, Messinger DS, Ibanez LV, Haltigan JD, Acosta SI, Buchman AC. Early social and emotional communication in the infant siblings of children with autism spectrum disorders: an examination of the broad phenotype. J Autism Dev Disord 2007; 37:122-132.

28.Goldberg AW, Jan/is KL, Osann K, Laulhere TM, Straub C. Brief report: early social communication behaviors in the younger siblings of children with autism. J Autism Dev Disord 2005; 35:657-664.

29.Constantino JN, Todd RD. Genetic structure of reciprocal social behavior. Am J Psychiatry 2000; 157:2043-2045.

30.Constantino JN, Przybeck T, Friesen D, Todd RD. Reciprocal social behavior in children with and without pervasive developmental disorders. J Dev Behav Pediatr 2000; 21:2-11.

31.Constantino J, Todd RD. Autistic traits in the general population: A twin study. Arch Gen Psychiatry 2003; 60:5824-5530.

32.Kaminsky L, Dewey D. Psychosocial adjustment in siblings of children with autism. J Child Psychol Psychiatry 2002; 43:225-232.

33.Williams P. Siblings and pediatric chronic illness: Review of the literature. Int J Nurs Stud 1997; 34:312-323.

34.Williams PD, Williams AR, Graff JC, Hanson S, Stanton A, Hafeman C, et al. Interrelationships among variables affecting well siblings and mothers in families of children with chronic illness or disability. J Behav Med 2002; 25:411-424.

35.Steiner H. Chronic Illness and Physical Disabilities. NE Alessi (Ed.), Handbook of Child and Adolescent Psychiatry, Canada, John Wiley and Sons, 1997, p.251-273.

36.Mates TE. Siblings of autistic children: Their adjustment and performance at home and in school. J Autism Dev Disord 1990; 20:545-553.

37.Rodrigue JR, Morgan SB, Geffken GR. Psychosocial adaptation of fathers of children with autism, down syndrome, and normal development. J Autism Dev Disord 1992; 22:249-264.

38.Sharpe D, Rossiter L. Siblings of children with a chronic illness: A meta-analysis. J Pediatr Psychol 2002; 27:699-710.

39.Gold N. Depression and social adjustment in siblings of boys with autism. J Autism Dev Disord 1993; 23:147-163.

40.Bagenholm A, Gillberg C. Psychosocial effects on siblings of children with autism and mental retar dation: A population-based study. J Merit Defic Res 1991; 35:291-307.

41.Ross P, Cuskelly M. Adjustment, sibling problems and coping strategies of brothers and sisters of children with autistic spectrum disorder. J Intellect Dev Disabil 2006; 31:77-86.

42.Pilowsky T, Yirmiya N, Doppelt 0, Gross-Tsur V, Shalev RS. Social and emotional adjustment of siblings of children with autism. J Child Psychol Psychiatry 2004; 45:855-865.

43.Scourfield J, Rice F, ThaparA, Harold GT, Martin N, McGuffin P. Depressive symptoms in children and adolescents: Changing aetiological influences with development. J Child Psychol Psychiatry 2003; 44:968-976.

44.Brent DA, Weersing VR. Depressive disorders. A Martin, FR Volkmar (Eds.), Lewis's Child and Adolescent Psychiatry, fourth ed., Philadelphia, Lippincott Williams and Wilkins, 2007, p. 503-513.

45.Daniels JL, Forssen U, Hultman CM, Cnattingius S, Savitz DA, Feychting M, et al. Parental psychiatric disorders associated with autism spectrum disorders in the offspring. Pediatrics 2008; 121:1357-1362.

46.Lobato D, Barbour L, Hall LJ, Miller CT. Psychosocial characteristics of handicapped and non-handicapped children. J Abnorm Child Psychol 1987; 3:329-338.

47.Smalley SL, McCracken K, Tanguay P. Autism, affective disorders, and social phobia. Am J Med Genet 1995; 60:19-26.

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Anadolu Psikiyatri Dergisi
  • ISSN: 1302-6631
  • Yayın Aralığı: Yılda 6 Sayı
  • Başlangıç: 2000
  • Yayıncı: AVES Yayıncılık

19.5b12.7b

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