The Chemical Composition of Essential Oils of Melissa officinalis subsp. altissima from Turkey

Melissa officinalis çok yıllık bir bitkidir ve Lamiaceae ailesinin bir üyesidir. Bu çalışmada, Türkiye doğal florası orjinli M. officinalis subsp altissima'nın kimyasal içeriğinin belirlenmesi amaçlanmıştır. Antalya doğal florasından toplanan tohumlar, sera koşulları ve deneme arazilerinde büyütülmüştür. Daha sonra kurutulan yapraklar Clevenger aparatı ile hidrodistile edildi ve numuneler gaz kromatografi ile analiz edildi. Toplamda % 92,5-94,7 oranında 23 bileşen belirlenmiştir. Tüm örneklerdeki yağlar karyofilen oksit (% 44,5-33,3), ?-copaene (%10,00-8,72) ve karyofilen (%5,578,26) gibi seskiterpenlerce zengindi. Karyofilen oksit her üç örnekte (sırasıyla % 44.5-33.4-38.58) 'de önemli bir bileşen olmuştur.

Türkiye'den Melissa officinalis subsp. altissima'nın Esansiyel Yağının Kimyasal Kompozisyonu

Melissa officinalis is a perennial herb and it is a member of the Lamiaceae family. In this study, the determining of chemical contents of M. officinalis subsp. altissima originated from the wild flora of Turkey was aimed. The seeds collected from the wild flora of Antalya, were grown in greenhouse conditions and experimental field. Then dried leaves were hydrodistillated with clevenger apparatus and samples were analysed with a gas chromatography. In total, twenty-three constituents were identified, representing 92.5-94.7% of the oils. The oils of all samples were rich in sesquiterpenes such as caryophyllene oxide (44.5-33.3%), ?-copaene (10.00-8.72%) and caryophyllene (5.57-8.26%). Caryophyllene oxide was the major component in all three samples (44.5-33.4-38.58%, respectively).

___

Adzet, T., Ponz R., Wolf E., Schulte E. 1992. Content and composition of M. officinalis oil in relation to leaf position and harvest time. Planta Med. 58: 562-56

Basta, A., Tzakou O., Couladis M. 2005. Composition of the leaves essential oil of Melissa officinalis s. l. fromGreece. Flavour Fragr. J., 20: 642-644.

Bolkent, S., Yanardag R., Karabulut O., Yesilyaprak B. 2005. Protective role of Melissa officinalis L. extract on liver of hyperlipidemic rats: a morphological and biochemical study. J. Ethnopharm., 99:397-398.

Craker, L.E., Simon J.E. 1992. Herbs, Spices and Medicinal Plants: Recent Advances in Botany, Horticulture, and Pharmacology. Volume 2. Oryx Press. USA.

Dawson, B.S.W., Franich R.A., Meder R. 1998. Essential oil of Melissa officinalis L. subsp. altissima (Sibthr. Et Smith). Arcang. Flav Fragr J 3: 167-170.

Geuenich, S., Goffinet C., Venzke S., Nolkemper S., Baumann I., Plinkert P., Reichling J., Keppler O.T. 2008. Aqueous extracts from peppermint, sage and lemon balm leaves displaypotent anti-HIV-1 activity by increasing the virion density. Retrovirology 5:27.

Hohmann J, Zupko I., Redei D. 1999. Protective effects of the aerial parts of Salvia officinalis, Melissa officinalis and Lavandula angustifolia and their constituents against enzymedependent and enzyme independent lipid peroxidation. Planta Med., 1999; 65: 576-578.

Lawrence B.M. 2008. "Progress in Essential Oils. Melissa or Lemon Balm Oil."Perf & Flav. 33 (Sept 2008), 66-70.

Meftahizade H, Sargsyan E., Moradkhani H. 2010. Investigation of antioxidantcapacity of Melissa officinalis L. essential oils. J. Med. Plant Res., 4(14): 1391-1395.

Moradkhani H., Sargsyan E., Bibak H., Naseri B., Sadat-Hosseini M., FayaziBarjin A., Meftahizade H. 2010. Melissa officinalis L., a valuable medicine plant. A review. J. Med. Plant Res., 4: 2753-2759.

Petersen, M., Simmonds, M.S.J. 2003. Molecules of interest: Rosmarinic acid. Phytochem., 62, 121-125.

Ribiero, M.A., Bernardo-Gil M.G., Esquivel M.M. 2001. Melissa officinalis L.: study of antioxidant activity in supercritical residues. J. Supercrit. Fluids. 21:51-60.

Saeb K., Gholamrezaee S. 2012. Variation of essential oil composition of Melissa officinalis L. leaves during different stages of plant growth, Asian Pac. J. Trop. Biol. 547-549.

Schultze, W., König W.A., Hilker A., Richter R. 1995. Melisseno le. Deutsche Apotheker Zeitung, 135, 557-577.

Shalaby, A.S, El-Gengaihi S., Khattab M. 1995. Oil of Melissa officinalis L., as affected by storage and herb drying. J. Essent. Oil Res. 7:667-669.

Tagashira M., Ohtake Y. 1998. A new antioxidative 1,3- benzodioxole fromMelissa officinalis. Planta Med., 64: 555-558.

Tucker, A.O., Debaggio T. 2000. The big book of herbs: a comprehensive illustrated reference to herbs of flavor and fragrance. Loveland, CO: Interweave Press.

Van den Berg T., Freundl E., Czygan F.C. 1997. Melissa officinalis subsp. altissima: characteristics of possibleadulteration of lemon balm. Pharm. 52: 803-808.

Weitzel, C., Petersen M. 2011. Cloning and characterisation of rosmarinic acid synthase from Melissa officinalis L. Phytochem., 72, 572-578.
Ziraat Fakültesi Dergisi-Cover
  • ISSN: 1304-9984
  • Yayın Aralığı: Yılda 2 Sayı
  • Başlangıç: 2006
  • Yayıncı: Isparta Uygulamalı Bilimler Üniversitesi