Ozan DOĞAN, Aşkı ELLİBEŞ KAYA, Cigdem PULATOGLU, Bertan AKAR, ALPER BAŞBUĞ, Eray ÇALIŞKAN

Mikro Besin Takviyesinin Maternal–Fetal Sonuçlara Etkisi: D vitamini, Kalsiyum ve Magnezyum

Amaç: Fetal ve maternal sağlığa olumlu etkileri olması nedeniyle gebelik döneminde artan ihtiyaçla orantılı olarak vitamin ve mineral desteğine ihtiyaç vardır. Bu çalışmada mikro besin takviyesi olarak D vitamini, Kalsiyum (Ca) ve Magnezyum (Mg) desteği alan gebelerin postnatal sonuçlarını ve gebelik komplikasyonlarını araştırmak amaçlandı. Gereçler ve Yöntem: Yapılan bu prospektif, longitudinal ve kalitatif çalışmaya Ocak 2016 ve Ocak 2018 tarihleri arasında 18-40 yaş arası toplam 2114 hasta dahil edilmiştir. Bulgular: Maternal yaş aralığı tüm hasta grupları için 28.11 ± 6.12‘ dir. Multivitamin kullanan grubun yaş ortalaması D vitamini grubuna göre daha düşük saptandı(p= 0.001). Yalnızca Mg ve D vitamini kullanan grupta yüksek lisans seviyesinde eğitim görenler daha fazlaydı(p=0.001). Mg, Ca, D vitamini ve multivitamin kullananımı ile gebelik komplikasyonları arasında anlamlı ilişki bulunamadı. Multivitamin kullanan gebelerde LGA daha fazla görüldü(p=0.038). İlk gebelik yaşı Ca ve mulivitamin kullanan grupta Mg ve D vitamini kullanan gruba göre daha düşük bulunmuştur(p=0.001). Sonuç: Annenin sağlıklı bir gebelik geçirmesi, maternal komplikasyonlardan korunması, fetusun büyüme ve gelişmesi için annenin düzenli beslenmesinin yanı sıra vitamin ve mineral takviyesi önemlidir. Bu takviyelerin literatürde gösterilmiş olan yararlarını desteklemek ve rutin kullanımda yer vermek için daha çok prospektif çalışmaya ihtiyaç vardır.

Effects of Micronutrient Supplement on Maternal and Fetal Outcomes: Vitamin D, Calcium and Magnesium

Objective: Due to the positive effects on fetal and maternal health, there is an increased need for vitamin and mineral supplements during pregnancy. In this study, it was aimed to investigate the postnatal outcomes and pregnancy complications of pregnant women who received vitamin D supplementation, calcium (Ca) and magnesium (Mg) as micronutrient supplement. Material and Methods: A total of 2114 patients aged between 18 and 40 years were included in this prospective, longitudinal and qualitative study between January 2016 and January 2018. Results: The mean maternal age was 28.11 ± 6.12 for all patient groups. The mean age of the group received multivitamins was lower than the vitamin D group (p = 0.001). In the group receiving only Mg and vitamin D supplements, the number of postgraduate educated patients were more (p = 0.001). There was no significant relationship between Mg, Ca, vitamin D and multivitamin use and pregnancy complications. LGA was more frequent in multivitamin-using group (p = 0.038). The first gestational age was found to be lower in Ca and multivamine group compared to the group receiving Mg and vitamin D supplement (p = 0.001). Conclusion: Vitamin and mineral supplementation as well as the regular daily nutrition is important not only for women to have a healthy pregnancy period without any maternal complications but also for growth and development of the fetus. More prospective studies with larger population are needed for supporting the benefits of these supplements and suggest their routine usage.

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