Demir eksikliği olan okul öncesi ve okul çağındaki çocukların serum çinko seviyelerinin değerlendirilmesi: Kesitsel vaka kontrol çalışması

Amaç: Dünyada hala ek sık gözlenen nutrisyonel eksiklikler demir ve çinko eksiklikleridir. Günümüzde bu nutrisyonel eksiklikler sadece gelişmekte olan ülkelerin değil tüm dünyanın önemli bir problemidir. Bu çalışmanın amacı, okul öncesi ve okul çağında demir eksikliği olan çocuklarda serum çinko seviyelerini karşılaştırmak ve eritrosit indekslerine olan etkilerini değerlendirmektir. Gereç ve Yöntemler: Çalışmaya Ocak 2011 ile Ağustos 2017 tarihleri arasında Gülhane Eğitim ve Araştırma Hastanesi çocuk hematolojisi polikliniğine başvuran, serum çinko ve demir düzeyleri bakılmış çocuklar dahil edildi. Hastalar okul öncesi (2-5 yaş) ve okul çağı (6-12 yaş) olarak 2 gruba ayrıldı ve grupların serum demir ve çinko düzeyleri değerlendirildi. Bulgular: Demir eksikliği anemisi olan gruplarda serum çinko düzeyleri, kontrol gruplarına göre istatistiksel olarak anlamlı bir şekilde düşük bulundu (p<0.05). Yapılan korelasyon analizinde serum çinko düzeyi ile hemoglobin düzeyi arasında istatistiksel olarak anlamlı ve pozitif yönlü bir korelasyon saptandı (p <0.05). Sonuç: Çalışma sonucunda elde ettiğimiz veriler çinkonun anemi için bağımsız bir risk faktörü olduğu yönündedir. Demir eksikliği anemisi olan çocuklarda demir tedavisine rağmen düzelmeyen anemi varlığında çinko desteği düşünülmelidir.

Anahtar Kelimeler:

Çinko, Demir eksikliği anemisi, Nutrisyonel eksiklik

The evaluation of zinc levels of preschool and school-aged children with iron deficiency: A cross-sectional case-control study

Abstract Objective: Iron and zinc deficiencies are still the most common nutritional deficiencies in the world. Nowadays, these nutritional deficiencies are a major problem not only for the developing countries but also for the whole world. The aim of this study was to compare serum zinc levels in children with iron deficiency in preschool and school-aged periods and to evaluate their effects on erythrocyte index. Material and Methods: The children, whose serum zinc and iron levels were checked, were recruited from outpatient pediatric hematology clinic at Gülhane Training and Research Hospital in the period from January 2011 till August 2017. Participants were divided into 2 groups as preschool (2-5 years) and school-aged (6-12 years) periods and serum iron and zinc levels were evaluated. Results: Serum zinc levels were significantly lower in the groups with iron deficiency anemia compared to the control groups (p<0.05). Correlation analysis revealed a statistically significant and positive correlation between serum zinc and hemoglobin levels (p <0.05). Conclusion: The data obtained from the study showed that serum zinc level is an independent risk factor for anemia. In children with iron deficiency anemia, zinc supplementation should be considered in the presence of anemia that does not improve despite the iron replacement.

Keywords:

Zinc, Iron deficiency anemia, Nutritional deficiency,

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